Interactor 1: IF2G (P32481)
Eukaryotic translation initiation factor 2 subunit gamma (eIF2-gamma) (EC 3.6.5.3)
Gene: GCD11

Interactor 2: IF5 (P38431)
Eukaryotic translation initiation factor 5 (eIF-5)
Gene: TIF5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 20485439, 21745818, 11018020, 10075937, 15838098, 16522633, 16990799, 16554755, 37968396, 14759368
Identification Methods pull down, anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains GTP_EFTU~eIF-5_eIF-2B, GTP_EFTU_D2~eIF-5_eIF-2B
Common GO terms GO:0001731 - formation of translation preinitiation complex
GO:0003743 - translation initiation factor activity
GO:0005525 - GTP binding
GO:0005829 - cytosol
GO:0031369 - translation initiation factor binding
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 527
Sc

1 405
+ Hs
+ Zm
+ Sc
+ Hs
+ Hv
+ Sc
+ Hv
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024