Interactor 1: HOG1 (P32485)
Mitogen-activated protein kinase HOG1 (MAP kinase HOG1) (EC 2.7.11.24) (High osmolarity glycerol response protein 1)
Gene: HOG1

Interactor 2: RCK2 (P38623)
Serine/threonine-protein kinase RCK2 (EC 2.7.11.1) (CAM kinase-like protein kinase CLK1)
Gene: RCK2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 11805837, 14735355, 10805732, 16554755, 26775127, 29738528, 18212044, 11344302, 18467557, 37968396, 20489023, 22615397
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology, protein complementation assay, two hybrid, enzymatic study, tandem affinity purification, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0007231 - osmosensory signaling pathway
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 435
Sc

1 610
+ Sc
+ Sp
+ At
+ At
+ At
+ At
+ Hs
+ At
+ Mm
+ At
+ At
+ Hs
+ Sp
+ At
+ At
+ At
+ Ce
+ Rn
+ Mm
+ Ce

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Last updated: 15 Jul 2024