HitPredict

Interactor 1: RPN12 (P32496)
26S proteasome regulatory subunit RPN12 (Nuclear integrity protein 1)
Gene: RPN12

Interactor 2: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.703

Property	Details
Experiments	11805826, 37968396, 20061387, 21619884, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 274 Sc			1 398
+	Hs
		819784 PSMD8_HUMAN (16-274): 3.08e-101: 300: 31.27		RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50
+	Rn
		1107992 Q3B8P5_RAT (16-274): 5.43e-98: 290: 30.89		RD23B_RAT (2-398): 7.78e-92: 284: 27.50
+	Hs
		819783 PSMD8_HUMAN (16-274): 3.08e-101: 300: 31.27		RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09
+	Hs
		819856 PSMD8_HUMAN (16-274): 3.08e-101: 300: 31.27		UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53
+	Hs
		819852 PSMD8_HUMAN (16-274): 3.08e-101: 300: 31.27		UBQL2_HUMAN (1-373): 8.68e-55: 192: 12.65
+	Hs
		819847 PSMD8_HUMAN (16-274): 3.08e-101: 300: 31.27		UBQL4_HUMAN (2-373): 1.16e-52: 186: 13.76
+	Sc
		691488 RPN12_YEAST (1-274): 3.71e-102: 300: 100.00		DSK2_YEAST (2-282): 4.39e-39: 145: 17.09
+	Dm
		1359548 Q9V436_DROME (1-274): 2.47e-78: 239: 26.72		Q9VWD9_DROME (2-374): 1.81e-47: 171: 13.38