HitPredict

Interactor 1: RPN12 (P32496)
26S proteasome regulatory subunit RPN12 (Nuclear integrity protein 1)
Gene: RPN12

Interactor 2: PRS6B (P33298)
26S proteasome regulatory subunit 6B homolog (Protein YNT1) (Tat-binding homolog 2)
Gene: RPT3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.60 0.716

The method score is based on:

Property Details
Experiments 11805826, 11805837, 37968396, 16429126, 11742986
Identification Methods tandem affinity purification, anti tag coimmunoprecipitation, affinity chromatography technology, two hybrid
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 274
Sc

1 428
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024