HitPredict

Interactor 1: RPN12 (P32496)
26S proteasome regulatory subunit RPN12 (Nuclear integrity protein 1)
Gene: RPN12

Interactor 2: RPN9 (Q04062)
26S proteasome regulatory subunit RPN9 (Proteasome non-ATPase subunit 7)
Gene: RPN9

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	1.00	0.945

The method score is based on:

Property	Details
Experiments	11805826, 16554755, 16429126, 19217412, 37968396, 22195964
Identification Methods	tandem affinity purification, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	CSN8_PSD8_EIF3K~PCI, CSN8_PSD8_EIF3K~Rpn9_C
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process GO:0008541 - proteasome regulatory particle, lid subcomplex and 2 others more... GO:0034515 - proteasome storage granule GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	274
Sc

1	393

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024