HitPredict

Interactor 1: NUP2 (P32499)
Nucleoporin NUP2 (Nuclear pore protein NUP2) (p95)
Gene: NUP2

Interactor 2: GSP1 (P32835)
GTP-binding nuclear protein GSP1/CNR1 (Chromosome stability protein 17) (GTPase Ran homolog) (Genetic suppressor of PRP20-1)
Gene: GSP1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.829

Property	Details
Experiments	7638224, 30837289, 27194810
Identification Methods	two hybrid, two hybrid array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Ran_BP1~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0016973 - poly(A)+ mRNA export from nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 720 Sc			1 219
+	At
		784994 RBP1A_ARATH (562-716): 9.7e-48: 170: 23.57		RAN1_ARATH (1-216): 6.84e-94: 275: 75.58
+	At
		784989 RBP1B_ARATH (559-716): 9.44e-43: 156: 21.25		RAN1_ARATH (1-216): 6.84e-94: 275: 75.58
+	At
		785000 RBP1A_ARATH (562-716): 9.7e-48: 170: 23.57		RAN2_ARATH (1-216): 1.74e-88: 261: 75.58
+	At
		1210455 RBP1A_ARATH (562-716): 9.7e-48: 170: 23.57		RAN3_ARATH (1-219): 5.37e-84: 250: 74.55
+	At
		784998 RBP1B_ARATH (559-716): 9.44e-43: 156: 21.25		RAN2_ARATH (1-216): 1.74e-88: 261: 75.58
+	At
		1210453 RBP1B_ARATH (559-716): 9.44e-43: 156: 21.25		RAN3_ARATH (1-219): 5.37e-84: 250: 74.55
+	Hs
		796725 RANG_HUMAN (562-720): 1.11e-48: 171: 23.78		RAN_HUMAN (1-216): 3.71e-76: 230: 80.56
+	Xl
		193796 O42193_XENLA (562-720): 7.58e-42: 153: 24.39		RAN_XENLA (1-216): 8.05e-77: 232: 81.02
+	Sc
		698847 YRB1_YEAST (524-720): 1.01e-38: 144: 22.50		GSP1_YEAST (1-219): 1.49e-79: 239: 100.00
+	Hs
		834710 RBP2_HUMAN (481-720): 7.57e-37: 151: 17.72		RAN_HUMAN (1-216): 3.71e-76: 230: 80.56
+	At
		784991 NU50A_ARATH (305-718): 5.6e-23: 104: 15.40		RAN1_ARATH (1-216): 6.84e-94: 275: 75.58
+	Hs
		919306 NUP50_HUMAN (324-717): 6.16e-34: 137: 14.29		RAN_HUMAN (1-216): 3.71e-76: 230: 80.56
+	Hs
		919269 RANB3_HUMAN (173-710): 3.91e-31: 130: 13.84		RAN_HUMAN (1-216): 3.71e-76: 230: 80.56
+	Sc
		698835 YRB2_YEAST (407-712): 2.67e-28: 118: 18.39		GSP1_YEAST (1-219): 1.49e-79: 239: 100.00
+	Sp
		660086 RANG_SCHPO (514-718): 9.51e-27: 110: 16.35		SPI1_SCHPO (5-219): 6.33e-77: 232: 88.37
+	Hs
		834576 NU153_HUMAN (184-601): 2.05e-21: 102: 18.00		RAN_HUMAN (1-216): 3.71e-76: 230: 80.56
+	Hs
		63882 RGPD3_HUMAN (92-286): 7.65e-20: 97.3: 16.08		RAN_HUMAN (1-216): 3.71e-76: 230: 80.56
+	Hs
		919141 RGPD4_HUMAN (92-286): 3.1e-19: 95.3: 16.08		RAN_HUMAN (1-216): 3.71e-76: 230: 80.56
+	Hs
		152774 RGPD8_HUMAN (92-286): 5.23e-19: 94.6: 15.58		RAN_HUMAN (1-216): 3.71e-76: 230: 80.56
+	Hs
		845340 NUP50_HUMAN (324-717): 6.16e-34: 137: 14.29		RAB7A_HUMAN (13-168): 4.23e-28: 107: 33.74