Protein: AP1B1
AP-1 complex subunit beta-1 (Beta-1-adaptin) (Clathrin assembly protein complex 1 beta-1 large chain) (Clathrin assembly protein large beta-1 chain)

Gene: AP1B1, APL2
Organism: Saccharomyces cerevisiae S288C
Interactions: 97
UniProt ID: P36000

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005905 - clathrin-coated pit
GO:0006886 - intracellular protein transport
GO:0006896 - Golgi to vacuole transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

778860

AP1M1
AP-1 complex subunit mu-1-I

12

20

Small-scale

0.984

High

778868

AP1G1
AP-1 complex subunit gamma-1

10

16

Small-scale

0.979

High

778839

APM2
Adaptin medium chain homolog APM2

8

20

Small-scale

0.974

High

763207

AP1S1
AP-1 complex subunit sigma-1

7

20

Small-scale

0.967

High

536104

ARF1
ADP-ribosylation factor 1

2

20

Small-scale

0.768

High

644750

CLH
Clathrin heavy chain

3

11

Small-scale

0.671

High

691603

AP2B
AP-2 complex subunit beta

1

15

Small-scale

0.618

High

778853

AP3B
AP-3 complex subunit beta

1

16

Small-scale

0.618

High

481996

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

2

0

High-throughput

0.602

High

778845

LAA1
AP-1 accessory protein LAA1

2

6

Small-scale

0.584

High

778862

ENT5
Epsin-5

2

20

Small-scale

0.584

High

778859

AP2S
AP-2 complex subunit sigma

1

20

Small-scale

0.575

High

434991

RS3
Small ribosomal subunit protein uS3

2

1

High-throughput

0.571

High

435887

RS13
Small ribosomal subunit protein uS15

2

1

High-throughput

0.571

High

778852

IRC6
Increased recombination centers protein 6

2

1

Small-scale

0.570

High

526377

HSP72
Heat shock protein SSA2

2

10

High-throughput

0.552

High

544425

SSB1
Ribosome-associated molecular chaperone SSB1

2

12

High-throughput

0.552

High

689373

RS7A
Small ribosomal subunit protein eS7A

2

0

High-throughput

0.547

High

392539

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.541

High

154149

RL36B
Large ribosomal subunit protein eL36B

1

0

High-throughput

0.513

High

432823

RL9A
Large ribosomal subunit protein uL6A

1

0

High-throughput

0.513

High

433002

RL6B
Large ribosomal subunit protein eL6B

1

0

High-throughput

0.513

High

503374

RL11A
Large ribosomal subunit protein uL5A

1

0

High-throughput

0.513

High

569964

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.513

High

689192

RL16B
Large ribosomal subunit protein uL13B

1

0

High-throughput

0.513

High

778838

YPT31
GTP-binding protein YPT31/YPT8

1

3

Small-scale

0.501

High

778873

INP53
Polyphosphatidylinositol phosphatase INP53

1

11

High-throughput

0.494

High

721835

XPO1
Exportin-1

1

16

High-throughput

0.489

High

778869

PIN2
[PSI+] induction protein 2

1

0

Small-scale

0.480

High

149688

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

383625

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.479

High

433563

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

441833

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

454982

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

502968

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.479

High

609217

CLC1
Clathrin light chain

1

12

Small-scale

0.479

High

709685

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

747795

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

753291

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

778252

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

778835

ALY1
Arrestin-related trafficking adapter 6

1

2

Small-scale

0.479

High

778836

GBLP
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.479

High

778840

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

778841

GGA2
ADP-ribosylation factor-binding protein GGA2

1

9

Small-scale

0.479

High

778844

ATC3
Phospholipid-transporting ATPase DRS2

1

2

Small-scale

0.479

High

778855

ALY2
Arrestin-related trafficking adapter 3

1

7

Small-scale

0.479

High

778856

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

778861

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

778863

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

778866

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

778870

CHS5
Chitin biosynthesis protein CHS5

1

1

Small-scale

0.479

High

778871

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

734653

IMB3
Importin subunit beta-3

1

1

High-throughput

0.464

High

410051

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

504147

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

512365

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

512929

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

514565

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

515074

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.458

High

674539

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

747284

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

394437

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

523576

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

531686

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.445

High

570236

RS17B
Small ribosomal subunit protein eS17B

1

2

High-throughput

0.445

High

579178

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.445

High

741327

HSP7F
Heat shock protein homolog SSE1

1

13

High-throughput

0.445

High

778843

RS14B
Small ribosomal subunit protein uS11B

1

1

High-throughput

0.445

High

778847

SSB2
Ribosome-associated molecular chaperone SSB2

1

12

High-throughput

0.445

High

778848

RL13B
Large ribosomal subunit protein eL13B

1

1

High-throughput

0.445

High

778857

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.445

High

778874

RL13A
Large ribosomal subunit protein eL13A

1

1

High-throughput

0.445

High

706750

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

748334

SC61A
Protein transport protein SEC61

1

2

High-throughput

0.437

High

778865

SGO1
Shugoshin

1

1

High-throughput

0.437

High

688860

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.426

High

778858

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.426

High

778872

RL7B
Large ribosomal subunit protein uL30B

1

0

High-throughput

0.426

High

778850

RGD2
Rho-GTPase-activating protein RGD2

1

6

High-throughput

0.417

High

778867

SOG2
Leucine-rich repeat-containing protein SOG2

1

1

High-throughput

0.417

High

427219

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.407

High

590601

HSP26
Heat shock protein 26

1

1

High-throughput

0.407

High

752107

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.407

High

778842

XDJ1
DnaJ protein homolog XDJ1

1

4

High-throughput

0.407

High

778846

PFD2
Prefoldin subunit 2

1

1

High-throughput

0.407

High

778849

JEM1
DnaJ-like chaperone JEM1

1

1

High-throughput

0.407

High

644904

RPA2
DNA-directed RNA polymerase I subunit RPA135

2

0

High-throughput

0.313

High

568926

INO4
Protein INO4

2

0

Small-scale

0.310

High

778851

MIL1
Probable lipase MIL1

1

0

High-throughput

0.269

Low

408472

GAL80
Galactose/lactose metabolism regulatory protein GAL80

1

0

High-throughput

0.265

Low

689774

INO2
Protein INO2

1

0

Small-scale

0.251

Low

613760

MDM10
Mitochondrial distribution and morphology protein 10

1

0

High-throughput

0.249

Low

744787

LAA2
Clathrin adapter accessory protein LAA2

1

0

High-throughput

0.249

Low

574871

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.238

Low

778837

RRN10
RNA polymerase I-specific transcription initiation factor RRN10

1

0

High-throughput

0.238

Low

778854

MRX5
MIOREX complex component 5

1

0

High-throughput

0.238

Low

778864

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025