Interactor 1: PRP19 (P32523)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase PRP19)
Gene: PRP19

Interactor 2: SYF1 (Q04048)
Pre-mRNA-splicing factor SYF1 (PRP19-associated complex protein 90) (Synthetic lethal with CDC40 protein 1)
Gene: SYF1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.760

The method score is based on:

Property Details
Experiments 11842115, 11884590, 11804584, 16429126, 16357217, 17515604, 19617314, 19704000, 20956557, 16554755, 37968396, 21576257
Identification Methods coimmunoprecipitation, affinity chromatography technology, two hybrid, biochemical, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000349 - generation of catalytic spliceosome for first transesterification step
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0005634 - nucleus
GO:0005829 - cytosol
and 1 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 503
Sc

1 859
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+ Sp
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+ Hs
+ Hs
+ Hs
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+ Dm
+ Dm

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Last updated: 15 Jul 2024