Interactor 1: PRP19 (P32523)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase PRP19)
Gene: PRP19
Interactor 2: CWC2 (Q12046)
Pre-mRNA-splicing factor CWC2 (Complexed with CEF1 protein 2) (PRP19-associated complex protein 40) (Synthetic lethal with CLF1 protein 3)
Gene: CWC2
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.761 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20462492, 11884590, 11804584, 16429126, 21386897, 12088152, 10092627, 18719252, 19016306, 37968396, 14690591 |
| Identification Methods | pull down, two hybrid, molecular sieving, cosedimentation in solution, affinity chromatography technology, biochemical, far western blotting, tandem affinity purification, two hybrid array |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000398 - mRNA splicing, via spliceosome GO:0000974 - Prp19 complex GO:0071006 - U2-type catalytic step 1 spliceosome |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
