HitPredict

Interactor 1: SPT16 (P32558)
FACT complex subunit SPT16 (Cell division control protein 68) (Facilitates chromatin transcription complex subunit SPT16) (Suppressor of Ty protein 16)
Gene: SPT16

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.977

Property	Details
Experiments	26804921, 16554755, 37968396, 22199229, 22922743, 23499444, 24248595, 33963860, 37850662, 22914091, 21179020
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Histone~Rtt106
Common GO terms	GO:0006325 - chromatin organization GO:0031298 - replication fork protection complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1035 Sc			1 136
+	Sc
		692744 SPT16_YEAST (1-1035): 0: 1136: 100.00		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Mm
		952764 SP16H_MOUSE (4-1028): 0: 1085: 32.38		H33_MOUSE (1-136): 1.25e-61: 187: 90.44
+	Hs
		935430 SP16H_HUMAN (4-1028): 0: 1082: 32.76		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		952728 SP16H_HUMAN (4-1028): 0: 1082: 32.76		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		1174703 SP16H_HUMAN (4-1028): 0: 1082: 32.76		H32_HUMAN (1-136): 6.6e-61: 185: 88.97
+	Hs
		1157245 SP16H_HUMAN (4-1028): 0: 1082: 32.76		H3C_HUMAN (1-136): 8.2e-59: 179: 86.03
+	Sp
		292839 SPT16_SCHPO (1-1032): 0: 1047: 45.64		H31_SCHPO (1-136): 1.17e-59: 182: 92.65
+	Hs
		828435 SP16H_HUMAN (4-1028): 0: 1082: 32.76		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Sp
		292845 SPT16_SCHPO (1-1032): 0: 1047: 45.64		CENPA_SCHPO (38-133): 9.18e-42: 136: 59.80