HitPredict

Interactor 1: SPT16 (P32558)
FACT complex subunit SPT16 (Cell division control protein 68) (Facilitates chromatin transcription complex subunit SPT16) (Suppressor of Ty protein 16)
Gene: SPT16

Interactor 2: RSC2 (Q06488)
Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2)
Gene: RSC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	14729968, 37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006368 - transcription elongation by RNA polymerase II
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1035 Sc			1 889
+	Hs
		1067214 SP16H_HUMAN (4-1028): 0: 1082: 32.76		BRD3_HUMAN (7-385): 2.06e-68: 243: 15.92
+	Sc
		692742 SPT16_YEAST (1-1035): 0: 1136: 100.00		BDF1_YEAST (26-219): 5.23e-19: 94.4: 12.63
+	Sc
		692739 SPT16_YEAST (1-1035): 0: 1136: 100.00		SPT7_YEAST (158-404): 1.37e-18: 93.5: 11.86
+	Hs
		999254 SP16H_HUMAN (4-1028): 0: 1082: 32.76		EP300_HUMAN (4-191): 1.16e-32: 139: 18.75
+	Hs
		631644 SP16H_HUMAN (4-1028): 0: 1082: 32.76		BRD2_HUMAN (2-255): 2.31e-29: 127: 15.89
+	Sc
		692720 SPT16_YEAST (1-1035): 0: 1136: 100.00		STH1_YEAST (275-377): 2.49e-11: 69.8: 24.27
+	Sc
		692881 SPT16_YEAST (1-1035): 0: 1136: 100.00		RSC4_YEAST (34-128): 1.91e-10: 66.7: 27.84
+	Hs
		245135 SP16H_HUMAN (4-1028): 0: 1082: 32.76		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		1342865 SP16H_HUMAN (4-1028): 0: 1082: 32.76		BRD7_HUMAN (2-258): 1.02e-24: 112: 12.36
+	Hs
		1262849 SP16H_HUMAN (4-1028): 0: 1082: 32.76		PHIP_HUMAN (19-293): 6.82e-20: 97.9: 12.77
+	Hs
		170522 SP16H_HUMAN (4-1028): 0: 1082: 32.76		TIF1A_HUMAN (47-132): 1.21e-11: 71: 32.22