Interactor 1: VPP1 (P32563)
V-type proton ATPase subunit a, vacuolar isoform (V-ATPase a 1 subunit) (V-ATPase 95 kDa subunit) (Vacuolar pH protein 1) (Vacuolar proton pump a subunit) (Vacuolar proton translocating ATPase subunit a 1)
Gene: VPH1

Interactor 2: VATH (P41807)
V-type proton ATPase subunit H (V-ATPase subunit H) (V-ATPase 54 kDa subunit) (Vacuolar proton pump subunit H)
Gene: VMA13

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 11592965, 19081055, 10747882, 18467557, 19299516, 37968396, 22615397, 23071676, 23142977
Identification Methods coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, affinity chromatography technology, protein complementation assay, two hybrid, unspecified method, x-ray crystallography, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains V-ATPase_H_C~V_ATPase_I, V-ATPase_H_N~V_ATPase_I
Common GO terms GO:0000329 - fungal-type vacuole membrane
GO:0007035 - vacuolar acidification
GO:0016471 - vacuolar proton-transporting V-type ATPase complex
GO:0046961 - proton-transporting ATPase activity, rotational mechanism
GO:1902600 - proton transmembrane transport
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 840
Sc

1 478
+ Sc
+ Hs

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Last updated: 15 Jul 2024