Protein: UPP
Uracil phosphoribosyltransferase (UPRTase) (EC 2.4.2.9) (UMP pyrophosphorylase)

Gene: UPP, FUR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 40
UniProt ID: P18562

Gene Ontology (top 5):
GO:0004845 - uracil phosphoribosyltransferase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0008655 - pyrimidine-containing compound salvage
GO:0044206 - UMP salvage

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

615290

URK1
Uridine kinase

5

15

High-throughput

0.925

High

615287

UPP
Uracil phosphoribosyltransferase

1

12

High-throughput

0.618

High

364915

KPYK1
Pyruvate kinase 1

2

0

High-throughput

0.585

High

486019

TBA1
Tubulin alpha-1 chain

1

2

High-throughput

0.536

High

386557

TBB
Tubulin beta chain

1

0

High-throughput

0.513

High

453409

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.513

High

615300

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.513

High

615302

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

615303

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.513

High

602305

PHO85
Cyclin-dependent protein kinase PHO85

1

2

High-throughput

0.501

High

615311

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.489

High

452474

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

1

High-throughput

0.479

High

439232

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

615292

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

615293

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.458

High

615294

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

615296

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

615307

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

543751

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

615298

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

615288

SIS1
Protein SIS1

1

1

High-throughput

0.437

High

615291

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

615304

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

394212

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

525868

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

591993

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

597027

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

597705

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

0

High-throughput

0.426

High

615310

GET3
ATPase GET3

2

0

High-throughput

0.307

High

615301

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.305

High

602106

SPO12
Sporulation-specific protein 12

1

0

Small-scale

0.265

Low

615306

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.265

Low

615289

CDC48
Cell division control protein 48

1

0

High-throughput

0.249

Low

615295

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

615297

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

615299

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

615305

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

615308

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

615309

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025