HitPredict

Interactor 1: RPN2 (P32565)
26S proteasome regulatory subunit RPN2
Gene: RPN2

Interactor 2: CUZ1 (P53899)
CDC48-associated ubiquitin-like/zinc finger protein 1 (CDC48-associated UBL/Zn-finger protein 1)
Gene: CUZ1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	37968396, 24297164
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 945 Sc			1 274
+	Hs
		1253516 PSMD1_HUMAN (3-926): 0: 1116: 39.98		ZFAN1_HUMAN (12-239): 2.67e-92: 275: 27.08
+	Mm
		1112129 PSMD1_MOUSE (3-926): 0: 1117: 40.39		ZFN2A_MOUSE (13-136): 2.39e-31: 116: 16.36
+	Hs
		1236207 PSMD1_HUMAN (3-926): 0: 1116: 39.98		ZFN2A_HUMAN (13-99): 1.82e-30: 112: 16.41
+	Mm
		1257516 PSMD2_MOUSE (9-770): 0: 757: 17.31		ZFN2A_MOUSE (13-136): 2.39e-31: 116: 16.36
+	Hs
		1027723 PSMD2_HUMAN (9-770): 0: 760: 17.31		ZFN2A_HUMAN (13-99): 1.82e-30: 112: 16.41
+	Hs
		1027734 PSMD2_HUMAN (9-770): 0: 760: 17.31		ZFN2B_HUMAN (13-100): 8.03e-27: 106: 14.73
+	Sc
		753903 RPN1_YEAST (9-573): 1.13e-134: 430: 17.33		CUZ1_YEAST (1-274): 1.66e-136: 387: 100.00