Interactor 1: MED22 (P32570)
Mediator of RNA polymerase II transcription subunit 22 (Mediator complex subunit 22) (Suppressor of RNA polymerase B 6)
Gene: SRB6

Interactor 2: MED8 (P38304)
Mediator of RNA polymerase II transcription subunit 8 (Mediator complex subunit 8)
Gene: MED8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.90 0.914

The method score is based on:

Property Details
Experiments 11805826, 16554755, 16263706, 27688401, 33933450, 37968396, 16429126, 24882805
Identification Methods tandem affinity purification, affinity chromatography technology, biochemical, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Med22~Med8
Common GO terms GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 3 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024