Interactor 1: MED18 (P32585)
Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (Suppressor of RNA polymerase B 5)
Gene: SRB5
Interactor 2: MED20 (P34162)
Mediator of RNA polymerase II transcription subunit 20 (Hyper-recombination suppressor protein 2) (Mediator complex subunit 20) (Suppressor of RNA polymerase B 2)
Gene: SRB2
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.90 | 0.933 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16964259, 9660972, 19934057, 11383511, 7877695, 16554755, 16429126, 17192271, 19057509, 37968396, 20123732, 22693636, 14759368, 15477388 |
| Identification Methods | pull down, x-ray crystallography, affinity chromatography technology, biochemical, tandem affinity purification, anti tag coimmunoprecipitation, two hybrid |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Med18~Med20 |
| Common GO terms | GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0016592 - mediator complex GO:0032968 - positive regulation of transcription elongation by RNA polymerase II and 4 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
