Interactor 1: MED18 (P32585)
Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (Suppressor of RNA polymerase B 5)
Gene: SRB5

Interactor 2: MED11 (Q99278)
Mediator of RNA polymerase II transcription subunit 11 (Mediator complex subunit 11)
Gene: MED11

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.90 0.915

The method score is based on:

Property Details
Experiments 11383511, 16554755, 16429126, 16962561, 17192271, 19057509, 37968396, 20123732
Identification Methods affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med11~Med18
Common GO terms GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 3 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024