Protein: ANK3
Ankyrin-3 (ANK-3) (Ankyrin-G)

Gene: ANK3
Organism: Homo sapiens
Interactions: 184
UniProt ID: Q12955

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0005200 - structural constituent of cytoskeleton
GO:0005764 - lysosome
GO:0005783 - endoplasmic reticulum
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1021468

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

3

11

High-throughput

0.861

High

131996

NCHL1
Neural cell adhesion molecule L1-like protein

2

8

High-throughput

0.811

High

1013379

NEXN
Nexilin

2

9

High-throughput

0.811

High

1021475

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

2

3

High-throughput

0.811

High

1021422

MICA3
[F-actin]-monooxygenase MICAL3

2

17

Small-scale

0.737

High

1021411

MK06
Mitogen-activated protein kinase 6

1

4

High-throughput

0.698

High

225136

MYPT2
Protein phosphatase 1 regulatory subunit 12B

1

19

High-throughput

0.691

High

386632

P53
Cellular tumor antigen p53

1

1

High-throughput

0.691

High

1021415

TTBK1
Tau-tubulin kinase 1

1

10

High-throughput

0.691

High

1021444

AJUBA
LIM domain-containing protein ajuba

1

3

High-throughput

0.691

High

942624

SRPK2
SRSF protein kinase 2

1

6

High-throughput

0.647

High

1021436

DOK4
Docking protein 4

3

0

High-throughput

0.638

High

1021451

PHAF1
Phagosome assembly factor 1

3

0

High-throughput

0.638

High

1021396

PWP1
Periodic tryptophan protein 1 homolog

2

3

High-throughput

0.628

High

1021423

RHG22
Rho GTPase-activating protein 22

2

12

High-throughput

0.628

High

1021441

RPGF5
Rap guanine nucleotide exchange factor 5

2

3

High-throughput

0.628

High

1021393

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

8

High-throughput

0.618

High

1021431

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

14

High-throughput

0.618

High

120412

RHOD
Rho-related GTP-binding protein RhoD

1

10

High-throughput

0.618

High

164611

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

20

High-throughput

0.618

High

166919

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

14

High-throughput

0.618

High

318120

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.618

High

338353

EGFR
Epidermal growth factor receptor

1

8

High-throughput

0.618

High

350123

RASK
GTPase KRas

1

8

High-throughput

0.618

High

374141

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.618

High

411697

LCK
Tyrosine-protein kinase Lck

1

4

High-throughput

0.618

High

433730

LYN
Tyrosine-protein kinase Lyn

1

4

High-throughput

0.618

High

507971

FGFR1
Fibroblast growth factor receptor 1

1

13

High-throughput

0.618

High

557108

PGFRA
Platelet-derived growth factor receptor alpha

1

6

High-throughput

0.618

High

665591

EPHB2
Ephrin type-B receptor 2

1

5

High-throughput

0.618

High

793293

MUC18
Cell surface glycoprotein MUC18

1

3

High-throughput

0.618

High

809108

UTRN
Utrophin

1

17

High-throughput

0.618

High

861724

PLK1
Serine/threonine-protein kinase PLK1

1

5

High-throughput

0.618

High

893947

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.618

High

900423

RHOA
Transforming protein RhoA

1

7

High-throughput

0.618

High

901141

RND3
Rho-related GTP-binding protein RhoE

1

11

High-throughput

0.618

High

915638

RHOB
Rho-related GTP-binding protein RhoB

1

7

High-throughput

0.618

High

925238

RAC1
Ras-related C3 botulinum toxin substrate 1

1

4

High-throughput

0.618

High

941688

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

1

3

High-throughput

0.618

High

950953

RHOG
Rho-related GTP-binding protein RhoG

1

4

High-throughput

0.618

High

963306

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

20

High-throughput

0.618

High

1021399

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

19

High-throughput

0.618

High

1021405

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.618

High

1021409

NTRK3
NT-3 growth factor receptor

1

11

High-throughput

0.618

High

1021421

RHOU
Rho-related GTP-binding protein RhoU

1

5

High-throughput

0.618

High

1021430

ARL14
ADP-ribosylation factor-like protein 14

1

2

High-throughput

0.618

High

1021458

SPTN4
Spectrin beta chain, non-erythrocytic 4

1

20

Small-scale

0.618

High

1021464

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

4

High-throughput

0.618

High

1021465

RHOF
Rho-related GTP-binding protein RhoF

1

10

High-throughput

0.618

High

590879

BTF3
Transcription factor BTF3

2

1

High-throughput

0.611

High

1021449

FEZ1
Fasciculation and elongation protein zeta-1

2

0

High-throughput

0.602

High

1021407

SMAD2
Mothers against decapentaplegic homolog 2

2

3

High-throughput

0.600

High

1021472

TNIK
TRAF2 and NCK-interacting protein kinase

1

10

High-throughput

0.590

High

912877

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.586

High

991944

SCN1B
Sodium channel subunit beta-1

1

0

Small-scale

0.586

High

547029

EZRI
Ezrin

2

9

High-throughput

0.584

High

716667

CTNA1
Catenin alpha-1

2

2

Small-scale

0.584

High

934710

H31
Histone H3.1

2

3

High-throughput

0.584

High

1021419

LIRA6
Leukocyte immunoglobulin-like receptor subfamily A member 6

2

4

High-throughput

0.584

High

1021404

PLEC
Plectin

1

14

Small-scale

0.573

High

1021477

PLAK2
PALM2-AKAP2 fusion protein

3

3

High-throughput

0.569

High

1021400

FLNC
Filamin-C

1

9

Small-scale

0.561

High

1021462

Q9H4D1
Protein kinase

1

16

High-throughput

0.555

High

1021420

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.553

High

119955

AP3B1
AP-3 complex subunit beta-1

1

2

Small-scale

0.552

High

1021442

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

0

Small-scale

0.537

High

496939

TAU
Microtubule-associated protein tau

1

16

High-throughput

0.536

High

713794

RYK
Tyrosine-protein kinase RYK

1

12

High-throughput

0.536

High

855628

KIF11
Kinesin-like protein KIF11

1

4

High-throughput

0.536

High

899624

FGF12
Fibroblast growth factor 12

1

9

High-throughput

0.536

High

1021403

TTLL4
Tubulin monoglutamylase TTLL4

1

1

High-throughput

0.536

High

832413

MCM2
DNA replication licensing factor MCM2

2

3

High-throughput

0.533

High

883496

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

19

High-throughput

0.528

High

241876

PQBP1
Polyglutamine-binding protein 1

1

0

High-throughput

0.513

High

1021438

BSND
Barttin

1

0

High-throughput

0.513

High

950161

SMAD3
Mothers against decapentaplegic homolog 3

1

3

High-throughput

0.508

High

306145

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

15

Small-scale

0.501

High

808109

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

6

High-throughput

0.501

High

808564

YAP1
Transcriptional coactivator YAP1

1

9

High-throughput

0.501

High

1021401

SCN5A
Sodium channel protein type 5 subunit alpha

1

5

Small-scale

0.501

High

1021453

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

1

15

Small-scale

0.501

High

1021461

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

15

Small-scale

0.501

High

826633

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.493

High

1021439

H1X
Histone H1.10

1

0

High-throughput

0.493

High

517228

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.489

High

1021446

IMP1L
Mitochondrial inner membrane protease subunit 1

1

2

High-throughput

0.489

High

119768

ARVC
Splicing regulator ARVCF

1

8

High-throughput

0.479

High

129747

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

8

High-throughput

0.479

High

178508

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

212816

STX6
Syntaxin-6

1

2

High-throughput

0.479

High

227310

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

229666

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

8

High-throughput

0.479

High

239121

CTND1
Catenin delta-1

1

8

High-throughput

0.479

High

279533

FLOT1
Flotillin-1

1

2

High-throughput

0.479

High

302510

CE152
Centrosomal protein of 152 kDa

1

7

High-throughput

0.479

High

417256

ENOA
Alpha-enolase

1

3

High-throughput

0.479

High

418218

NPM
Nucleophosmin

1

1

High-throughput

0.479

High

434183

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

13

High-throughput

0.479

High

438117

HS90B
Heat shock protein HSP 90-beta

1

7

High-throughput

0.479

High

506579

BCR
Breakpoint cluster region protein

1

12

High-throughput

0.479

High

515147

ADHX
Alcohol dehydrogenase class-3

1

1

High-throughput

0.479

High

521899

CADH1
Cadherin-1

1

1

High-throughput

0.479

High

537887

KPYM
Pyruvate kinase PKM

1

1

High-throughput

0.479

High

577019

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

1

High-throughput

0.479

High

588596

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

1

High-throughput

0.479

High

614305

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

2

High-throughput

0.479

High

670006

MARCS
Myristoylated alanine-rich C-kinase substrate

1

6

High-throughput

0.479

High

717038

CTNB1
Catenin beta-1

1

4

High-throughput

0.479

High

779322

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

816341

NPBW2
Neuropeptides B/W receptor type 2

1

1

High-throughput

0.479

High

819566

KCNC1
Potassium voltage-gated channel subfamily C member 1

1

1

Small-scale

0.479

High

923657

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

High-throughput

0.479

High

974788

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

980743

TLE3
Transducin-like enhancer protein 3

1

6

High-throughput

0.479

High

1001573

FCHO2
F-BAR domain only protein 2

1

4

High-throughput

0.479

High

1017613

STX4
Syntaxin-4

1

5

High-throughput

0.479

High

1021391

ABR
Active breakpoint cluster region-related protein

1

14

High-throughput

0.479

High

1021392

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

10

Small-scale

0.479

High

1021395

IQGA2
Ras GTPase-activating-like protein IQGAP2

1

4

High-throughput

0.479

High

1021397

CUL3
Cullin-3

1

7

High-throughput

0.479

High

1021410

OCLN
Occludin

1

2

High-throughput

0.479

High

1021414

RHG21
Rho GTPase-activating protein 21

1

10

High-throughput

0.479

High

1021417

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.479

High

1021418

RNF43
E3 ubiquitin-protein ligase RNF43

1

2

High-throughput

0.479

High

1021424

PHLB2
Pleckstrin homology-like domain family B member 2

1

12

High-throughput

0.479

High

1021425

LIPB1
Liprin-beta-1

1

4

High-throughput

0.479

High

1021429

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

4

High-throughput

0.479

High

1021433

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

1021434

DLG5
Disks large homolog 5

1

6

High-throughput

0.479

High

1021435

OTU7A
OTU domain-containing protein 7A

1

8

High-throughput

0.479

High

1021440

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

1021445

LRCH3
DISP complex protein LRCH3

1

4

High-throughput

0.479

High

1021447

DOCK7
Dedicator of cytokinesis protein 7

1

2

High-throughput

0.479

High

1021450

LZTS2
Leucine zipper putative tumor suppressor 2

1

12

High-throughput

0.479

High

1021456

WWTR1
WW domain-containing transcription regulator protein 1

1

9

High-throughput

0.479

High

1021459

VP33B
Vacuolar protein sorting-associated protein 33B

1

1

High-throughput

0.479

High

1021460

DNJC5
DnaJ homolog subfamily C member 5

1

3

High-throughput

0.479

High

1021466

E41LA
Band 4.1-like protein 4A

1

10

High-throughput

0.479

High

1021469

EP15R
Epidermal growth factor receptor substrate 15-like 1

1

12

High-throughput

0.479

High

1021470

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1021474

SMG5
Nonsense-mediated mRNA decay factor SMG5

1

2

High-throughput

0.479

High

1021478

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

3

High-throughput

0.479

High

1021479

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

9

High-throughput

0.479

High

1021480

DTNA
Dystrobrevin alpha

1

5

High-throughput

0.479

High

1021481

NS1BP
Influenza virus NS1A-binding protein

1

2

High-throughput

0.479

High

396926

HMGN1
Non-histone chromosomal protein HMG-14

1

1

High-throughput

0.470

High

124846

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

0

High-throughput

0.458

High

305433

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

329690

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.458

High

536352

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.458

High

567034

CXA1
Gap junction alpha-1 protein

1

0

High-throughput

0.458

High

796735

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.458

High

919954

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

1021416

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

0

High-throughput

0.458

High

1021437

PI3R5
Phosphoinositide 3-kinase regulatory subunit 5

1

0

High-throughput

0.458

High

1021471

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

0

High-throughput

0.458

High

1021394

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

3

High-throughput

0.457

High

1021454

NDEL1
Nuclear distribution protein nudE-like 1

1

8

High-throughput

0.457

High

1021467

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.457

High

87570

C9JWL8
Leukocyte immunoglobulin like receptor B3

1

4

High-throughput

0.445

High

239969

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.445

High

252779

LIRB3
Leukocyte immunoglobulin-like receptor subfamily B member 3

1

4

High-throughput

0.445

High

1021455

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

15

Small-scale

0.445

High

1021457

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

15

Small-scale

0.445

High

1021476

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.445

High

708430

MCM4
DNA replication licensing factor MCM4

1

3

High-throughput

0.437

High

1021398

CUL4A
Cullin-4A

1

7

High-throughput

0.437

High

1021402

MCM6
DNA replication licensing factor MCM6

1

3

High-throughput

0.437

High

1021413

SKT
Sickle tail protein homolog

1

4

High-throughput

0.437

High

1021443

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1021448

RING2
E3 ubiquitin-protein ligase RING2

1

4

High-throughput

0.437

High

1021452

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.437

High

1021463

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

2

High-throughput

0.437

High

1021426

PRSR2
Proline and serine-rich protein 2

2

0

High-throughput

0.328

High

1021432

UXS1
UDP-glucuronic acid decarboxylase 1

2

0

High-throughput

0.328

High

1021406

NAB2
NGFI-A-binding protein 2

2

0

High-throughput

0.316

High

1021412

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

132465

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

171211

CTDSL
CTD small phosphatase-like protein

1

0

High-throughput

0.249

Low

610844

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

0

High-throughput

0.249

Low

1021408

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low

1021427

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1021428

CCD71
Coiled-coil domain-containing protein 71

1

0

High-throughput

0.249

Low

1021473

TF3C4
General transcription factor 3C polypeptide 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024