HitPredict

Interactor 1: HSP7F (P32589)
Heat shock protein homolog SSE1 (Chaperone protein MSI3)
Gene: SSE1

Interactor 2: PSA4 (P40303)
Proteasome subunit alpha type-4 (Macropain subunit PRE6) (Multicatalytic endopeptidase complex subunit PRE6) (Proteasome component PRE6) (Proteinase YSCE subunit PRE6)
Gene: PRE6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	19536198, 16429126
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0010499 - proteasomal ubiquitin-independent protein catabolic process GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 693 Sc			1 254
+	Hs
		156208 HSP7C_HUMAN (2-645): 0: 851: 27.04		PSA7_HUMAN (4-234): 3.74e-95: 280: 58.01
+	Hs
		503469 HSP7C_HUMAN (2-645): 0: 851: 27.04		PSA4_HUMAN (3-233): 8.68e-91: 270: 31.49
+	Hs
		503791 HSP7C_HUMAN (2-645): 0: 851: 27.04		PSA6_HUMAN (2-239): 6.82e-91: 270: 29.75
+	Hs
		503466 HSP7C_HUMAN (2-645): 0: 851: 27.04		PSA1_HUMAN (2-249): 6.06e-90: 268: 31.35
+	Hs
		503490 HSP7C_HUMAN (2-645): 0: 851: 27.04		PSA5_HUMAN (2-236): 2.2e-90: 268: 32.92
+	Hs
		503467 HSP7C_HUMAN (2-645): 0: 851: 27.04		PSA2_HUMAN (3-236): 1.56e-45: 154: 38.14
+	Dm
		505051 HSP7D_DROME (2-644): 0: 835: 27.08		PSA2_DROME (4-214): 9.25e-44: 149: 40.28
+	Sc
		494109 HSP72_YEAST (1-382): 1.15e-71: 246: 36.82		PSA4_YEAST (1-254): 1.72e-97: 287: 100.00
+	Sc
		491397 HSP71_YEAST (1-382): 7.01e-71: 244: 36.55		PSA4_YEAST (1-254): 1.72e-97: 287: 100.00
+	Sc
		490393 HSP71_YEAST (1-382): 7.01e-71: 244: 36.55		PSA3_YEAST (4-207): 3.34e-40: 140: 35.29