Protein: ARF1
ADP-ribosylation factor 1 (EC 3.6.5.2)

Gene: ARF1
Organism: Homo sapiens
Interactions: 210
UniProt ID: P84077

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000287 - magnesium ion binding
GO:0002090 - regulation of receptor internalization
GO:0003723 - RNA binding
GO:0003924 - GTPase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

862153

ARFP2
Arfaptin-2

4

10

Small-scale

0.892

High

950568

GGA3
ADP-ribosylation factor-binding protein GGA3

4

20

Small-scale

0.891

High

950575

GGA1
ADP-ribosylation factor-binding protein GGA1

4

20

Small-scale

0.887

High

950545

CYH2
Cytohesin-2

4

14

Small-scale

0.885

High

863200

COPB
Coatomer subunit beta

4

20

Small-scale

0.874

High

862219

ARFP1
Arfaptin-1

3

10

Small-scale

0.847

High

950523

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

2

20

Small-scale

0.799

High

950579

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

2

17

Small-scale

0.799

High

950578

AP4E1
AP-4 complex subunit epsilon-1

2

20

Small-scale

0.783

High

119709

AP4M1
AP-4 complex subunit mu-1

2

2

Small-scale

0.757

High

950473

ARF1
ADP-ribosylation factor 1

2

14

Small-scale

0.755

High

950485

PLD1
Phospholipase D1

2

2

Small-scale

0.754

High

950511

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

2

7

High-throughput

0.737

High

950577

ASAP1
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

1

14

Small-scale

0.692

High

574647

ARF4
ADP-ribosylation factor 4

1

15

High-throughput

0.691

High

897349

ARF3
ADP-ribosylation factor 3

1

15

High-throughput

0.691

High

950474

ARF5
ADP-ribosylation factor 5

1

13

High-throughput

0.691

High

119949

AP3B1
AP-3 complex subunit beta-1

1

20

Small-scale

0.647

High

212618

AP1G1
AP-1 complex subunit gamma-1

1

20

Small-scale

0.647

High

229657

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

9

Small-scale

0.647

High

950481

AP1B1
AP-1 complex subunit beta-1

1

20

Small-scale

0.647

High

950539

PKHA8
Pleckstrin homology domain-containing family A member 8

1

7

Small-scale

0.647

High

950547

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

17

Small-scale

0.647

High

950574

GGA2
ADP-ribosylation factor-binding protein GGA2

1

20

Small-scale

0.647

High

350070

RASK
GTPase KRas

3

20

High-throughput

0.640

High

656996

5HT2A
5-hydroxytryptamine receptor 2A

2

3

Small-scale

0.624

High

150204

AP3D1
AP-3 complex subunit delta-1

1

20

High-throughput

0.618

High

239455

PLPL9
85/88 kDa calcium-independent phospholipase A2

1

2

Small-scale

0.618

High

818919

COPD
Coatomer subunit delta

1

7

High-throughput

0.618

High

912846

ARF6
ADP-ribosylation factor 6

1

17

High-throughput

0.618

High

950502

RHG21
Rho GTPase-activating protein 21

1

8

Small-scale

0.618

High

950522

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

20

High-throughput

0.618

High

950560

PKHA4
Pleckstrin homology domain-containing family A member 4

1

19

High-throughput

0.618

High

950563

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

20

High-throughput

0.618

High

950582

GIT1
ARF GTPase-activating protein GIT1

1

14

Small-scale

0.618

High

950585

COPG1
Coatomer subunit gamma-1

1

18

Small-scale

0.618

High

159356

PLD2
Phospholipase D2

2

2

Small-scale

0.602

High

950584

TRPV2
Transient receptor potential cation channel subfamily V member 2

1

1

Small-scale

0.590

High

591812

RAB4A
Ras-related protein Rab-4A

2

20

High-throughput

0.584

High

950505

LTOR1
Ragulator complex protein LAMTOR1

2

6

High-throughput

0.584

High

383738

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

15

High-throughput

0.576

High

950498

RHG31
Rho GTPase-activating protein 31

2

9

High-throughput

0.571

High

591209

ACM3
Muscarinic acetylcholine receptor M3

1

3

Small-scale

0.561

High

950581

WBP11
WW domain-binding protein 11

1

3

High-throughput

0.541

High

128535

DNM1L
Dynamin-1-like protein

1

1

High-throughput

0.536

High

547784

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

4

High-throughput

0.536

High

581671

VCAM1
Vascular cell adhesion protein 1

1

3

High-throughput

0.536

High

601212

VDAC1
Voltage-dependent anion-selective channel protein 1

1

8

High-throughput

0.536

High

950548

PARK7
Parkinson disease protein 7

1

1

High-throughput

0.536

High

644007

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.518

High

950526

NOA1
Nitric oxide-associated protein 1

1

0

High-throughput

0.518

High

950535

T106A
Transmembrane protein 106A

1

0

High-throughput

0.518

High

950572

DUX4
Double homeobox protein 4

1

3

High-throughput

0.516

High

506382

RALA
Ras-related protein Ral-A

1

18

Small-scale

0.501

High

622670

ERD21
ER lumen protein-retaining receptor 1

1

3

Small-scale

0.501

High

887139

AP3S2
AP-3 complex subunit sigma-2

1

10

Small-scale

0.501

High

950503

GORAB
RAB6-interacting golgin

1

2

Small-scale

0.501

High

950508

DEN1B
DENN domain-containing protein 1B

1

7

Small-scale

0.501

High

950528

DEN1A
DENN domain-containing protein 1A

1

7

Small-scale

0.501

High

950540

SCYL1
N-terminal kinase-like protein

1

5

Small-scale

0.501

High

950521

FBXW8
F-box/WD repeat-containing protein 8

1

3

Small-scale

0.500

High

452739

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.489

High

149608

COPE
Coatomer subunit epsilon

1

3

Small-scale

0.481

High

125370

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

5

Small-scale

0.479

High

178480

STX7
Syntaxin-7

1

6

High-throughput

0.479

High

318101

DIRA3
GTP-binding protein Di-Ras3

1

18

High-throughput

0.479

High

346520

MYC
Myc proto-oncogene protein

1

4

Small-scale

0.479

High

348612

RASN
GTPase NRas

1

20

High-throughput

0.479

High

359331

K1C14
Keratin, type I cytoskeletal 14

1

6

High-throughput

0.479

High

363072

FINC
Fibronectin

1

3

High-throughput

0.479

High

374049

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

11

High-throughput

0.479

High

380591

K2C1
Keratin, type II cytoskeletal 1

1

2

High-throughput

0.479

High

390177

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

4

High-throughput

0.479

High

433694

LYN
Tyrosine-protein kinase Lyn

1

3

High-throughput

0.479

High

445030

K1C16
Keratin, type I cytoskeletal 16

1

6

High-throughput

0.479

High

475624

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

High-throughput

0.479

High

514814

MPRI
Cation-independent mannose-6-phosphate receptor

1

6

High-throughput

0.479

High

518639

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.479

High

527390

LAMP2
Lysosome-associated membrane glycoprotein 2

1

10

High-throughput

0.479

High

530620

ITA4
Integrin alpha-4

1

7

High-throughput

0.479

High

531347

K1C10
Keratin, type I cytoskeletal 10

1

8

High-throughput

0.479

High

567007

CXA1
Gap junction alpha-1 protein

1

3

High-throughput

0.479

High

573658

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

5

High-throughput

0.479

High

591546

RAB3B
Ras-related protein Rab-3B

1

18

High-throughput

0.479

High

623872

KPCL
Protein kinase C eta type

1

1

High-throughput

0.479

High

625356

CDK2
Cyclin-dependent kinase 2

1

4

High-throughput

0.479

High

669977

MARCS
Myristoylated alanine-rich C-kinase substrate

1

4

High-throughput

0.479

High

702028

RL9
Large ribosomal subunit protein uL6

1

1

High-throughput

0.479

High

714513

GRK5
G protein-coupled receptor kinase 5

1

2

High-throughput

0.479

High

716990

CTNB1
Catenin beta-1

1

1

High-throughput

0.479

High

723029

OPRM
Mu-type opioid receptor

1

4

Small-scale

0.479

High

735919

ATPG
ATP synthase subunit gamma, mitochondrial

1

1

High-throughput

0.479

High

736401

RL4
Large ribosomal subunit protein uL4

1

1

High-throughput

0.479

High

760008

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

809263

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

9

Small-scale

0.479

High

838768

EMD
Emerin

1

2

High-throughput

0.479

High

844480

RAB5C
Ras-related protein Rab-5C

1

18

High-throughput

0.479

High

845435

RAB9A
Ras-related protein Rab-9A

1

18

High-throughput

0.479

High

890101

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.479

High

895036

RAB2A
Ras-related protein Rab-2A

1

20

High-throughput

0.479

High

908372

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

914004

RB11A
Ras-related protein Rab-11A

1

17

High-throughput

0.479

High

915603

RHOB
Rho-related GTP-binding protein RhoB

1

18

High-throughput

0.479

High

916518

RS6
Small ribosomal subunit protein eS6

1

1

High-throughput

0.479

High

940393

CXAR
Coxsackievirus and adenovirus receptor

1

7

High-throughput

0.479

High

946723

TMF1
TATA element modulatory factor

1

2

High-throughput

0.479

High

950475

VIGLN
Vigilin

1

6

High-throughput

0.479

High

950476

LAT1
Large neutral amino acids transporter small subunit 1

1

7

High-throughput

0.479

High

950480

CKAP4
Cytoskeleton-associated protein 4

1

8

High-throughput

0.479

High

950482

STX4
Syntaxin-4

1

8

High-throughput

0.479

High

950484

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

9

High-throughput

0.479

High

950486

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

950487

STIM1
Stromal interaction molecule 1

1

1

High-throughput

0.479

High

950491

RBM39
RNA-binding protein 39

1

7

High-throughput

0.479

High

950492

EPN4
Clathrin interactor 1

1

5

High-throughput

0.479

High

950493

GOGB1
Golgin subfamily B member 1

1

3

High-throughput

0.479

High

950494

CUL7
Cullin-7

1

1

High-throughput

0.479

High

950495

RAB35
Ras-related protein Rab-35

1

20

High-throughput

0.479

High

950496

TRIPB
Thyroid receptor-interacting protein 11

1

10

High-throughput

0.479

High

950497

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

6

Small-scale

0.479

High

950499

PKHG6
Pleckstrin homology domain-containing family G member 6

1

4

High-throughput

0.479

High

950500

PKHG4
Puratrophin-1

1

4

High-throughput

0.479

High

950504

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

950507

CDC73
Parafibromin

1

4

High-throughput

0.479

High

950510

RICTR
Rapamycin-insensitive companion of mTOR

1

5

High-throughput

0.479

High

950515

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

5

High-throughput

0.479

High

950517

HORN
Hornerin

1

3

High-throughput

0.479

High

950518

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

1

High-throughput

0.479

High

950519

K319L
Dyslexia-associated protein KIAA0319-like protein

1

4

High-throughput

0.479

High

950520

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.479

High

950524

DHB11
Estradiol 17-beta-dehydrogenase 11

1

5

High-throughput

0.479

High

950527

GOGA5
Golgin subfamily A member 5

1

12

High-throughput

0.479

High

950529

PARD3
Partitioning defective 3 homolog

1

7

High-throughput

0.479

High

950531

AKAP1
A-kinase anchor protein 1, mitochondrial

1

4

High-throughput

0.479

High

950532

REQU
Zinc finger protein ubi-d4

1

3

High-throughput

0.479

High

950533

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

4

High-throughput

0.479

High

950536

LRC59
Leucine-rich repeat-containing protein 59

1

5

High-throughput

0.479

High

950537

CHM4C
Charged multivesicular body protein 4c

1

5

High-throughput

0.479

High

950543

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

11

High-throughput

0.479

High

950544

MMS19
MMS19 nucleotide excision repair protein homolog

1

1

High-throughput

0.479

High

950550

BAG1
BAG family molecular chaperone regulator 1

1

3

High-throughput

0.479

High

950551

PTN18
Tyrosine-protein phosphatase non-receptor type 18

1

5

High-throughput

0.479

High

950553

OSB10
Oxysterol-binding protein-related protein 10

1

2

High-throughput

0.479

High

950554

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.479

High

950558

S38A1
Sodium-coupled neutral amino acid symporter 1

1

3

High-throughput

0.479

High

950559

CHM4B
Charged multivesicular body protein 4b

1

5

High-throughput

0.479

High

950564

FBX6
F-box only protein 6

1

1

High-throughput

0.479

High

950565

DUS22
Dual specificity protein phosphatase 22

1

9

High-throughput

0.479

High

950569

WWOX
WW domain-containing oxidoreductase

1

2

High-throughput

0.479

High

950570

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

950571

PI4KB
Phosphatidylinositol 4-kinase beta

1

2

High-throughput

0.479

High

950576

RAB21
Ras-related protein Rab-21

1

20

High-throughput

0.479

High

950580

LAMP3
Lysosome-associated membrane glycoprotein 3

1

10

High-throughput

0.479

High

329638

AGR2
Anterior gradient protein 2 homolog

1

5

High-throughput

0.470

High

305413

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

398862

HMGN2
Non-histone chromosomal protein HMG-17

1

0

High-throughput

0.458

High

575011

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.458

High

881610

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

907845

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.458

High

911340

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.458

High

950477

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.458

High

950479

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.458

High

950534

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.458

High

950542

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

950561

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

239937

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.445

High

401844

JUN
Transcription factor Jun

1

5

High-throughput

0.445

High

496842

TAU
Microtubule-associated protein tau

1

13

High-throughput

0.445

High

717697

BMI1
Polycomb complex protein BMI-1

1

4

High-throughput

0.445

High

893269

SNP25
Synaptosomal-associated protein 25

1

3

Small-scale

0.445

High

894718

RAB8A
Ras-related protein Rab-8A

1

18

Small-scale

0.445

High

950483

STK4
Serine/threonine-protein kinase 4

1

8

High-throughput

0.445

High

950488

CUL3
Cullin-3

1

3

High-throughput

0.445

High

950490

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

3

High-throughput

0.445

High

950541

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

9

High-throughput

0.445

High

950549

SEPT5
Septin-5

1

3

Small-scale

0.445

High

950556

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

3

High-throughput

0.445

High

294712

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.437

High

390823

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

4

High-throughput

0.437

High

552492

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

650955

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

720228

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

785855

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

High-throughput

0.437

High

950478

P2R3A
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha

1

1

High-throughput

0.437

High

950509

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

3

High-throughput

0.437

High

950512

RHG36
Rho GTPase-activating protein 36

1

12

High-throughput

0.437

High

950513

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

950516

GOLI
E3 ubiquitin-protein ligase RNF130

1

12

High-throughput

0.437

High

950525

RN149
E3 ubiquitin-protein ligase RNF149

1

11

High-throughput

0.437

High

950530

TM263
Transmembrane protein 263

1

3

High-throughput

0.437

High

950552

OVOL2
Transcription factor Ovo-like 2

1

3

Small-scale

0.437

High

950555

LNP
Endoplasmic reticulum junction formation protein lunapark

1

2

High-throughput

0.437

High

950557

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

5

High-throughput

0.437

High

950566

TB22B
TBC1 domain family member 22B

1

10

High-throughput

0.437

High

950567

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.437

High

950573

HOOK1
Protein Hook homolog 1

1

3

High-throughput

0.437

High

950583

AAR2
Protein AAR2 homolog

1

3

High-throughput

0.437

High

795495

RAD52
DNA repair protein RAD52 homolog

1

0

Small-scale

0.426

High

146

A0A024R6X4
PLEKHG4

1

4

High-throughput

0.407

High

950489

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

8

High-throughput

0.407

High

725769

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.279

Low

950514

COX15
Heme A synthase COX15

1

0

High-throughput

0.279

Low

950538

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

0

High-throughput

0.279

Low

100680

APRIO
Alternative prion protein

1

0

Small-scale

0.249

Low

795102

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.249

Low

950506

TET2
Methylcytosine dioxygenase TET2

1

0

Small-scale

0.249

Low

950546

SEC62
Translocation protein SEC62

1

0

High-throughput

0.249

Low

950562

SHCAF
SIN3-HDAC complex-associated factor

1

0

Small-scale

0.249

Low

950501

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024