HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: CDK5 (Q00535)
Cyclin-dependent kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Cyclin-dependent-like kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)
Gene: CDK5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 292
+	Hs
		667544 RFA1_HUMAN (1-616): 0: 781: 100.00		CDK2_HUMAN (1-292): 7.63e-142: 402: 59.39
+	Hs
		443196 RFA1_HUMAN (1-616): 0: 781: 100.00		CDK1_HUMAN (1-289): 2.07e-133: 381: 56.01
+	Hs
		694948 RFA1_HUMAN (1-616): 0: 781: 100.00		CDK7_HUMAN (2-292): 3.01e-127: 367: 45.24
+	Hs
		695227 RFA1_HUMAN (1-616): 0: 781: 100.00		CDK16_HUMAN (1-286): 1.11e-115: 343: 57.99