HitPredict

Interactor 1: SWI3 (P32591)
SWI/SNF complex subunit SWI3 (Transcription factor TYE2) (Transcription regulatory protein SWI3)
Gene: SWI3

Interactor 2: GCN5 (Q03330)
Histone acetyltransferase GCN5 (EC 2.3.1.48) (Histone crotonyltransferase GCN5) (EC 2.3.1.-)
Gene: GCN5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	21734642, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Acetyltransf_1~Myb_DNA-binding
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006338 - chromatin remodeling GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 825 Sc			1 439
+	Sc
		797934 RSC8_YEAST (211-824): 1.16e-120: 377: 23.40		GCN5_YEAST (1-439): 0: 543: 100.00
+	Mm
		1149045 MYSM1_MOUSE (52-478): 3.93e-69: 246: 16.19		KAT2B_MOUSE (1-430): 0: 535: 39.59
+	Hs
		1198566 TAD2B_HUMAN (472-793): 3.63e-69: 236: 12.54		KAT2B_HUMAN (2-430): 0: 527: 39.22
+	Mm
		1208540 TAD2A_MOUSE (472-786): 1.33e-60: 213: 10.73		KAT2B_MOUSE (1-430): 0: 535: 39.59
+	Hs
		1198565 TAD2B_HUMAN (472-793): 3.63e-69: 236: 12.54		KAT2A_HUMAN (14-430): 5.17e-171: 502: 38.30
+	Hs
		1138818 MYSM1_HUMAN (23-441): 1.34e-56: 210: 14.86		KAT2B_HUMAN (2-430): 0: 527: 39.22
+	Hs
		266399 TAD2A_HUMAN (472-786): 3.21e-59: 209: 10.73		KAT2B_HUMAN (2-430): 0: 527: 39.22
+	Hs
		266398 TAD2A_HUMAN (472-786): 3.21e-59: 209: 10.73		KAT2A_HUMAN (14-430): 5.17e-171: 502: 38.30
+	Mm
		1208541 TAD2A_MOUSE (472-786): 1.33e-60: 213: 10.73		KAT2A_MOUSE (14-430): 1.8e-168: 495: 37.97
+	At
		1308007 TAD2B_ARATH (459-804): 1.47e-67: 234: 16.31		GCN5_ARATH (67-429): 1.31e-156: 456: 44.68
+	At
		1308015 TAD2A_ARATH (436-780): 6.06e-58: 209: 15.57		GCN5_ARATH (67-429): 1.31e-156: 456: 44.68
+	Dm
		1212009 TAD2B_DROME (474-800): 1.5e-60: 216: 11.75		Q9VTZ1_DROME (42-432): 3.07e-148: 443: 38.56
+	Dm
		283714 TAD2B_DROME (474-800): 1.5e-60: 216: 11.75		O76216_DROME (42-432): 6.05e-148: 442: 38.31
+	At
		1275616 SWI3C_ARATH (173-733): 7.99e-137: 427: 18.21		GTE11_ARATH (249-435): 1.86e-39: 151: 24.61
+	At
		1195144 SWI3B_ARATH (257-743): 3.02e-94: 305: 22.07		GTE11_ARATH (249-435): 1.86e-39: 151: 24.61
+	At
		1258938 SWI3A_ARATH (293-731): 8.84e-89: 291: 20.59		GTE11_ARATH (249-435): 1.86e-39: 151: 24.61
+	Sc
		728711 RSC8_YEAST (211-824): 1.16e-120: 377: 23.40		BDF1_YEAST (349-432): 9.45e-09: 59.7: 38.37
+	Mm
		1145012 KDM1A_MOUSE (154-451): 4.23e-56: 209: 12.17		TIF1A_MOUSE (225-438): 6.05e-49: 181: 22.83
+	Hs
		232126 KDM1A_HUMAN (153-451): 2.6e-57: 213: 12.46		EP300_HUMAN (253-431): 1.9e-39: 153: 23.40
+	Hs
		231897 KDM1A_HUMAN (153-451): 2.6e-57: 213: 12.46		BRD4_HUMAN (256-438): 5.45e-36: 143: 25.53