Protein: CHMP5
Charged multivesicular body protein 5 (Chromatin-modifying protein 5) (SNF7 domain-containing protein 2) (Vacuolar protein sorting-associated protein 60) (Vps60) (hVps60)

Gene: CHMP5
Organism: Homo sapiens
Interactions: 90
UniProt ID: Q9NZZ3

Gene Ontology (top 5):
GO:0000421 - autophagosome membrane
GO:0000776 - kinetochore
GO:0000815 - ESCRT III complex
GO:0001778 - plasma membrane repair
GO:0001919 - regulation of receptor recycling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1445996

VTA1
Vacuolar protein sorting-associated protein VTA1 homolog

5

7

Small-scale

0.927

High

1433095

CHM4B
Charged multivesicular body protein 4b

3

18

High-throughput

0.858

High

221888

CHM2A
Charged multivesicular body protein 2a

2

19

High-throughput

0.811

High

1439645

CHM1A
Charged multivesicular body protein 1a

2

20

High-throughput

0.811

High

1453653

CHMP3
Charged multivesicular body protein 3

2

20

High-throughput

0.811

High

925688

IST1
IST1 homolog

1

18

High-throughput

0.691

High

276928

VPS4B
Vacuolar protein sorting-associated protein 4B

3

20

High-throughput

0.675

High

1273184

CHM1B
Charged multivesicular body protein 1b

1

20

High-throughput

0.656

High

1417744

CHM4A
Charged multivesicular body protein 4a

1

20

High-throughput

0.656

High

1453649

CHMP5
Charged multivesicular body protein 5

1

19

High-throughput

0.656

High

425656

ISG15
Ubiquitin-like protein ISG15

3

2

Small-scale

0.640

High

1384282

SH3K1
SH3 domain-containing kinase-binding protein 1

2

5

High-throughput

0.628

High

1453651

VPS4A
Vacuolar protein sorting-associated protein 4A

2

20

Small-scale

0.611

High

340685

STABP
STAM-binding protein

2

11

Small-scale

0.586

High

1218801

BROX
BRO1 domain-containing protein BROX

1

14

Small-scale

0.578

High

1438562

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

1

Small-scale

0.573

High

1357851

MITD1
MIT domain-containing protein 1

1

4

High-throughput

0.573

High

170391

AURKA
Aurora kinase A

1

3

High-throughput

0.536

High

483239

CLCA
Clathrin light chain A

1

7

High-throughput

0.536

High

483408

CLCB
Clathrin light chain B

1

7

High-throughput

0.536

High

530476

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.536

High

650997

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

14

High-throughput

0.536

High

856957

BAG6
Large proline-rich protein BAG6

1

4

High-throughput

0.536

High

1049845

1433F
14-3-3 protein eta

1

11

High-throughput

0.536

High

1116075

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

7

High-throughput

0.536

High

1120372

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

15

High-throughput

0.536

High

1367815

TFG
Protein TFG

1

7

High-throughput

0.536

High

903503

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

4

High-throughput

0.508

High

992097

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.508

High

828258

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

12

Small-scale

0.501

High

1365991

APBP2
Amyloid protein-binding protein 2

1

1

High-throughput

0.494

High

1453652

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

0

High-throughput

0.493

High

1389515

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

5

High-throughput

0.489

High

1350284

URGCP
Up-regulator of cell proliferation

1

0

High-throughput

0.486

High

1414400

PDC10
Programmed cell death protein 10

1

0

High-throughput

0.486

High

133810

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

1

High-throughput

0.479

High

169775

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

5

Small-scale

0.479

High

243160

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

346429

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

10

High-throughput

0.479

High

358816

LDHA
L-lactate dehydrogenase A chain

1

4

High-throughput

0.479

High

556383

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

583112

VATB1
V-type proton ATPase subunit B, kidney isoform

1

6

High-throughput

0.479

High

630066

BTF3
Transcription factor BTF3

1

4

High-throughput

0.479

High

681734

PSA4
Proteasome subunit alpha type-4

1

4

High-throughput

0.479

High

799534

BRCA1
Breast cancer type 1 susceptibility protein

1

5

High-throughput

0.479

High

981146

H2B1C
Histone H2B type 1-C/E/F/G/I

1

9

High-throughput

0.479

High

986778

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

High-throughput

0.479

High

995860

ACTC
Actin, alpha cardiac muscle 1

1

4

High-throughput

0.479

High

1033277

EWS
RNA-binding protein EWS

1

5

High-throughput

0.479

High

1094641

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

12

High-throughput

0.479

High

1324926

RHG18
Rho GTPase-activating protein 18

1

2

High-throughput

0.479

High

1330959

CGAS
Cyclic GMP-AMP synthase

1

5

High-throughput

0.479

High

1360688

SYNE2
Nesprin-2

1

15

High-throughput

0.479

High

1400341

FMNL2
Formin-like protein 2

1

1

High-throughput

0.479

High

1407486

TS101
Tumor susceptibility gene 101 protein

1

5

Small-scale

0.479

High

1431554

VP33B
Vacuolar protein sorting-associated protein 33B

1

1

High-throughput

0.479

High

1453650

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

913867

ZN142
Zinc finger protein 142

1

1

High-throughput

0.464

High

295888

FACE1
CAAX prenyl protease 1 homolog

1

0

High-throughput

0.458

High

643107

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.458

High

1402457

PEBP4
Phosphatidylethanolamine-binding protein 4

1

0

High-throughput

0.458

High

1258201

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

1

7

Small-scale

0.457

High

993781

UBC9
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.457

High

1054519

EXOS9
Exosome complex component RRP45

1

1

High-throughput

0.457

High

1119713

CDK13
Cyclin-dependent kinase 13

1

4

High-throughput

0.457

High

1231812

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

1

6

High-throughput

0.457

High

1352898

TP4AP
Short transient receptor potential channel 4-associated protein

1

3

High-throughput

0.457

High

255250

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

6

High-throughput

0.445

High

765951

BMI1
Polycomb complex protein BMI-1

1

7

High-throughput

0.445

High

800582

VATA
V-type proton ATPase catalytic subunit A

1

10

High-throughput

0.445

High

1119341

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

2

High-throughput

0.445

High

589899

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

696717

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

769375

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

1276889

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1312291

MIRO2
Mitochondrial Rho GTPase 2

1

10

High-throughput

0.437

High

1405568

TBX5
T-box transcription factor TBX5

1

3

High-throughput

0.437

High

297871

PIAS2
E3 SUMO-protein ligase PIAS2

1

1

High-throughput

0.417

High

1404467

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.417

High

887279

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.373

High

1351652

TCP1L
T-complex protein 10A homolog 1

2

0

High-throughput

0.328

High

1430837

STMN4
Stathmin-4

2

0

High-throughput

0.328

High

1051155

ZNF91
Zinc finger protein 91

1

0

High-throughput

0.265

Low

1366377

TF3A
Transcription factor IIIA

1

0

High-throughput

0.265

Low

377762

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

1226547

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

1347615

NEIL3
Endonuclease 8-like 3

1

0

High-throughput

0.249

Low

1394372

HPDL
4-hydroxyphenylpyruvate dioxygenase-like protein

1

0

High-throughput

0.249

Low

1447093

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025