HitPredict

Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: PRPK (Q96S44)
EKC/KEOPS complex subunit TP53RK (EC 3.6.-.-) (Atypical serine/threonine protein kinase TP53RK) (Nori-2) (TP53-regulating kinase) (EC 2.7.11.1) (p53-related protein kinase)
Gene: TP53RK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 616 Hs			1 253
+	Hs
		691997 RFA1_HUMAN (1-616): 0: 781: 100.00		MARK3_HUMAN (10-249): 5.66e-82: 261: 18.33
+	Hs
		169961 RFA1_HUMAN (1-616): 0: 781: 100.00		AURKA_HUMAN (1-245): 1.99e-80: 248: 16.06
+	Hs
		695394 RFA1_HUMAN (1-616): 0: 781: 100.00		KCC2D_HUMAN (28-187): 1.48e-21: 94.8: 18.41
+	Hs
		695393 RFA1_HUMAN (1-616): 0: 781: 100.00		KCC2G_HUMAN (28-187): 4e-21: 93.7: 18.18
+	Zm
		2179 A0A1D6EZA2_MAIZE (83-505): 1.9e-78: 267: 14.57		A0A0B4J3D8_MAIZE (24-251): 3.29e-82: 255: 13.39