HitPredict

Interactor 1: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Interactor 2: DDI1 (P40087)
DNA damage-inducible protein 1 (EC 3.4.23.-) (v-SNARE-master 1)
Gene: DDI1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.863

Property	Details
Experiments	11805121, 11700052, 16405905
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	UBA~UBA, UBA~ubiquitin, UBA~XPC-binding
Common GO terms	GO:0005737 - cytoplasm GO:0030674 - protein-macromolecule adaptor activity GO:0031593 - polyubiquitin modification-dependent protein binding GO:0043130 - ubiquitin binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 398 Sc			1 428
+	Hs
		872275 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		DDI2_HUMAN (12-325): 4.26e-146: 423: 34.37
+	Hs
		1136657 UBQL2_HUMAN (1-373): 8.68e-55: 192: 12.65		DDI2_HUMAN (12-325): 4.26e-146: 423: 34.37
+	Zm
		80385 B6TNT9_MAIZE (4-397): 5.53e-43: 159: 11.99		K7UR93_MAIZE (3-427): 3.34e-159: 456: 31.88
+	Hs
		803572 BAG6_HUMAN (2-369): 6.15e-43: 162: 11.96		DDI2_HUMAN (12-325): 4.26e-146: 423: 34.37
+	Dm
		1375389 Q9VXF9_DROME (2-397): 3.6e-54: 187: 14.32		Q9VXF9_DROME (3-428): 2.36e-130: 385: 27.58
+	Dm
		1362834 Q9VCD5_DROME (2-398): 1.55e-52: 178: 20.55		Q9VXF9_DROME (3-428): 2.36e-130: 385: 27.58
+	Dm
		547961 RS27A_DROME (2-89): 9.05e-39: 138: 22.73		Q9VXF9_DROME (3-428): 2.36e-130: 385: 27.58
+	Ce
		1089021 Q23451_CAEEL (1-398): 7.52e-61: 201: 24.13		DDI1_CAEEL (89-342): 7.47e-85: 266: 31.82