HitPredict

Interactor 1: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Interactor 2: DSK2 (P48510)
Ubiquitin domain-containing protein DSK2
Gene: DSK2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	11805121
Identification Methods	two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0030674 - protein-macromolecule adaptor activity GO:0031593 - polyubiquitin modification-dependent protein binding GO:0036503 - ERAD pathway
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 398 Sc			1 373
+	Sc
		697061 RAD23_YEAST (1-398): 8.4e-101: 306: 100.00		RAD23_YEAST (2-370): 3.25e-51: 177: 15.25
+	Hs
		872124 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		RD23A_HUMAN (1-370): 2.33e-57: 192: 16.92
+	Hs
		872123 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		RD23A_HUMAN (1-370): 2.33e-57: 192: 16.92
+	Hs
		872241 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		RD23B_HUMAN (3-369): 2.45e-50: 175: 13.70
+	Sp
		251965 RHP23_SCHPO (2-398): 4.18e-81: 255: 33.25		DSK2_SCHPO (3-370): 1.05e-52: 180: 36.04
+	Hs
		872301 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		UBL7_HUMAN (23-371): 5.9e-41: 150: 15.79
+	Hs
		872201 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		UBL7_HUMAN (23-371): 5.9e-41: 150: 15.79
+	Hs
		872137 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		RL40_HUMAN (3-73): 2.22e-28: 109: 36.11
+	Hs
		872317 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		UBQL2_HUMAN (73-370): 4.05e-19: 90.7: 20.25
+	Hs
		872229 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		UBQL1_HUMAN (73-370): 3.03e-20: 94.2: 17.61
+	Hs
		872226 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		UBQL2_HUMAN (73-370): 4.05e-19: 90.7: 20.25
+	Hs
		872162 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		NEDD8_HUMAN (5-71): 1.4e-21: 89.7: 39.71
+	Hs
		872222 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		UBQL4_HUMAN (74-370): 4.18e-18: 87.6: 13.64
+	Hs
		803807 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		BAG6_HUMAN (2-313): 7.67e-32: 129: 20.74
+	Hs
		924435 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		RL40_HUMAN (3-73): 2.22e-28: 109: 36.11
+	Hs
		1355403 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		UBQL2_HUMAN (73-370): 4.05e-19: 90.7: 20.25
+	Hs
		1079632 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		NEDD8_HUMAN (5-71): 1.4e-21: 89.7: 39.71
+	Hs
		1345051 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		UBQL4_HUMAN (74-370): 4.18e-18: 87.6: 13.64