HitPredict

Interactor 1: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.975

Property	Details
Experiments	12200147, 9490418, 11805826, 12589471, 10394357, 11389845, 37968396, 20516210, 20059542, 16429126, 16712842
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, pull down, biochemical, two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 398 Sc			1 405
+	Rn
		907221 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		PRS8_RAT (3-405): 1.36e-129: 380: 73.95
+	Hs
		872249 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS8_HUMAN (3-405): 1.36e-129: 380: 73.95
+	Rn
		1104198 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		Q32PW9_RAT (27-402): 1.28e-124: 366: 43.88
+	Hs
		872134 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PRS8_HUMAN (3-405): 1.36e-129: 380: 73.95
+	Rn
		1117333 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		PRS6B_RAT (13-397): 1.88e-123: 365: 41.04
+	Hs
		872250 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS10_HUMAN (20-402): 2.79e-124: 366: 43.34
+	Rn
		906973 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		PRS4_RAT (2-395): 3.16e-121: 360: 44.92
+	Hs
		872248 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS4_HUMAN (2-395): 3.16e-121: 360: 44.92
+	Hs
		798621 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS6B_HUMAN (13-397): 3.38e-118: 351: 41.04
+	Hs
		872133 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PRS4_HUMAN (2-395): 3.16e-121: 360: 44.92
+	Sc
		697092 RAD23_YEAST (1-398): 8.4e-101: 306: 100.00		PRS4_YEAST (72-395): 3.99e-106: 321: 49.85
+	Sc
		697067 RAD23_YEAST (1-398): 8.4e-101: 306: 100.00		PRS7_YEAST (83-391): 1.16e-104: 318: 51.78
+	Hs
		798620 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PRS6B_HUMAN (13-397): 3.38e-118: 351: 41.04
+	Rn
		1117330 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		PRS7_RAT (60-390): 7.75e-109: 328: 50.75
+	Dm
		1359291 Q9V3W9_DROME (2-398): 1.44e-82: 260: 24.77		Q9V405_DROME (5-397): 1.09e-118: 352: 39.50
+	Hs
		730225 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PRS7_HUMAN (60-390): 7.87e-110: 331: 51.05
+	Hs
		730224 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PRS7_HUMAN (60-390): 7.87e-110: 331: 51.05
+	Hs
		906946 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PRS4_HUMAN (2-395): 3.16e-121: 360: 44.92
+	Hs
		798782 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PRS6B_HUMAN (13-397): 3.38e-118: 351: 41.04
+	Hs
		730383 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PRS7_HUMAN (60-390): 7.87e-110: 331: 51.05