Protein: GNL3L
Guanine nucleotide-binding protein-like 3-like protein

Gene: GNL3L
Organism: Homo sapiens
Interactions: 125
UniProt ID: Q9NVN8

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005525 - GTP binding
GO:0005654 - nucleoplasm
GO:0005697 - telomerase holoenzyme complex
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

343816

LDOC1
Protein LDOC1

4

0

High-throughput

0.663

High

373284

MYC
Myc proto-oncogene protein

3

7

High-throughput

0.640

High

1249448

OLFM4
Olfactomedin-4

3

0

High-throughput

0.638

High

1450715

TRM7
tRNA

2

4

High-throughput

0.628

High

725465

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

1

High-throughput

0.606

High

1063648

GOGA2
Golgin subfamily A member 2

2

2

High-throughput

0.606

High

562442

LAMP2
Lysosome-associated membrane glycoprotein 2

2

0

High-throughput

0.602

High

981134

H2B1C
Histone H2B type 1-C/E/F/G/I

2

6

High-throughput

0.584

High

269398

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

991731

DYL1
Dynein light chain 1, cytoplasmic

2

0

High-throughput

0.580

High

1238132

HMBX1
Homeobox-containing protein 1

2

0

High-throughput

0.580

High

653737

PROZ
Vitamin K-dependent protein Z

2

1

High-throughput

0.574

High

771249

APJ
Apelin receptor

2

2

High-throughput

0.574

High

1411335

LZTS2
Leucine zipper putative tumor suppressor 2

1

2

High-throughput

0.573

High

397053

ESR1
Estrogen receptor

2

10

High-throughput

0.571

High

928566

TERF1
Telomeric repeat-binding factor 1

1

1

Small-scale

0.561

High

1206004

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

2

High-throughput

0.553

High

1419239

TRI54
Tripartite motif-containing protein 54

2

6

High-throughput

0.553

High

560922

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

0

High-throughput

0.549

High

74624

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

3

High-throughput

0.536

High

174121

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.536

High

182803

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.536

High

445271

S10A6
Protein S100-A6

1

1

High-throughput

0.536

High

682629

S100P
Protein S100-P

1

1

High-throughput

0.536

High

694017

RL10
Large ribosomal subunit protein uL16

1

5

High-throughput

0.536

High

854341

KI67
Proliferation marker protein Ki-67

1

2

High-throughput

0.536

High

859088

RL27A
Large ribosomal subunit protein uL15

1

2

High-throughput

0.536

High

1027792

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

6

High-throughput

0.536

High

1407307

CML1
Chemerin-like receptor 1

1

2

High-throughput

0.536

High

1447232

EXOS5
Exosome complex component RRP46

1

1

High-throughput

0.536

High

1450722

OAS3
2'-5'-oligoadenylate synthase 3

1

3

High-throughput

0.536

High

1028413

MDM2
E3 ubiquitin-protein ligase Mdm2

1

2

Small-scale

0.534

High

1450720

TMED5
Transmembrane emp24 domain-containing protein 5

2

1

High-throughput

0.533

High

414716

P53
Cellular tumor antigen p53

1

3

Small-scale

0.515

High

1208901

H2B2F
Histone H2B type 2-F

1

6

High-throughput

0.515

High

1022488

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.513

High

1311529

BBS7
BBSome complex member BBS7

1

0

High-throughput

0.513

High

1349133

F174A
Membrane protein FAM174A

1

0

High-throughput

0.513

High

1450719

SMC3
Structural maintenance of chromosomes protein 3

1

0

High-throughput

0.513

High

349346

NUD14
Uridine diphosphate glucose pyrophosphatase NUDT14

1

0

High-throughput

0.493

High

848731

MAGA9
Melanoma-associated antigen 9

1

2

High-throughput

0.489

High

1270856

SV2A
Synaptic vesicle glycoprotein 2A

1

1

High-throughput

0.489

High

1281485

ZN467
Zinc finger protein 467

1

2

High-throughput

0.489

High

911402

IMA5
Importin subunit alpha-5

1

2

High-throughput

0.481

High

1450714

TFP11
Tuftelin-interacting protein 11

1

1

High-throughput

0.481

High

129476

MEN1
Menin

1

2

High-throughput

0.479

High

141135

NOP56
Nucleolar protein 56

1

7

High-throughput

0.479

High

162974

TERT
Telomerase reverse transcriptase

1

1

Small-scale

0.479

High

191122

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

2

High-throughput

0.479

High

218841

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

376007

RASK
GTPase KRas

1

1

High-throughput

0.479

High

406708

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.479

High

696659

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

697270

APEX1
DNA repair nuclease/redox regulator APEX1

1

2

High-throughput

0.479

High

769326

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

799513

BRCA1
Breast cancer type 1 susceptibility protein

1

2

High-throughput

0.479

High

831517

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

920306

PLK1
Serine/threonine-protein kinase PLK1

1

1

High-throughput

0.479

High

941279

IF6
Eukaryotic translation initiation factor 6

1

5

High-throughput

0.479

High

968460

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

2

High-throughput

0.479

High

971167

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

973604

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.479

High

978347

RHOB
Rho-related GTP-binding protein RhoB

1

7

High-throughput

0.479

High

979292

RS6
Small ribosomal subunit protein eS6

1

5

High-throughput

0.479

High

982849

RS24
Small ribosomal subunit protein eS24

1

2

High-throughput

0.479

High

985027

RL31
Large ribosomal subunit protein eL31

1

6

High-throughput

0.479

High

998866

H31
Histone H3.1

1

7

High-throughput

0.479

High

1024872

VIGLN
Vigilin

1

4

High-throughput

0.479

High

1107266

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

1114432

CUL3
Cullin-3

1

4

High-throughput

0.479

High

1133005

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

6

High-throughput

0.479

High

1138095

TNIP1
TNFAIP3-interacting protein 1

1

7

High-throughput

0.479

High

1140931

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

1194410

LARP7
La-related protein 7

1

8

High-throughput

0.479

High

1235541

IFIX
Pyrin and HIN domain-containing protein 1

1

5

High-throughput

0.479

High

1289660

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.479

High

1328972

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

3

High-throughput

0.479

High

1334991

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

1338396

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1352782

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

1367401

ESR2
Estrogen receptor beta

1

9

High-throughput

0.479

High

1368643

KAT6A
Histone acetyltransferase KAT6A

1

10

High-throughput

0.479

High

1384828

OTUL
Ubiquitin thioesterase otulin

1

1

Small-scale

0.479

High

1393750

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

1397484

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.479

High

1418615

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

8

High-throughput

0.479

High

1420955

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

1429945

BRD8
Bromodomain-containing protein 8

1

8

High-throughput

0.479

High

1446399

BRD7
Bromodomain-containing protein 7

1

11

High-throughput

0.479

High

1447329

ANLN
Anillin

1

3

High-throughput

0.479

High

1450716

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1450721

ZN330
Zinc finger protein 330

1

2

High-throughput

0.479

High

458496

ADRB2
Beta-2 adrenergic receptor

1

0

Small-scale

0.460

High

1103405

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.460

High

65823

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

0

High-throughput

0.458

High

574124

GLUT4
Solute carrier family 2, facilitated glucose transporter member 4

1

0

High-throughput

0.458

High

639411

5NTD
5'-nucleotidase

1

0

High-throughput

0.458

High

774665

BASI
Basigin

1

0

High-throughput

0.458

High

1178419

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1405565

TBX5
T-box transcription factor TBX5

1

0

High-throughput

0.458

High

1429370

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

344338

PTBP3
Polypyrimidine tract-binding protein 3

1

2

High-throughput

0.445

High

1132450

CASP8
Caspase-8

1

1

High-throughput

0.445

High

1209719

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

1227559

A16L1
Autophagy-related protein 16-1

1

9

High-throughput

0.445

High

174622

TRI66
Tripartite motif-containing protein 66

1

7

High-throughput

0.437

High

294410

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.437

High

342338

BRD1
Bromodomain-containing protein 1

1

6

High-throughput

0.437

High

1255779

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

1434031

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

1450718

TSP50
Probable threonine protease PRSS50

1

3

High-throughput

0.437

High

844975

EAA2
Excitatory amino acid transporter 2

1

0

High-throughput

0.426

High

1339467

TOIP2
Torsin-1A-interacting protein 2

1

0

High-throughput

0.426

High

1437633

ROP1A
Ropporin-1A

4

0

High-throughput

0.364

High

749287

CD70
CD70 antigen

2

0

High-throughput

0.328

High

1412154

ERP44
Endoplasmic reticulum resident protein 44

2

0

High-throughput

0.328

High

260806

RAMP2
Receptor activity-modifying protein 2

1

0

High-throughput

0.279

Low

880209

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.279

Low

1350901

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1225089

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

0

High-throughput

0.268

Low

1450717

DCDC2
Doublecortin domain-containing protein 2

1

0

High-throughput

0.268

Low

327701

UBL3
Ubiquitin-like protein 3

1

0

Small-scale

0.249

Low

1249261

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1433275

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

1

0

High-throughput

0.249

Low

1288457

SO6A1
Solute carrier organic anion transporter family member 6A1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025