Interactor 1: BRR2 (P32639)
Pre-mRNA-splicing helicase BRR2 (EC 3.6.4.13) (Protein Snu246)
Gene: BRR2

Interactor 2: SN114 (P36048)
Pre-mRNA-splicing factor SNU114 (114 kDa U5 small nuclear ribonucleoprotein component) (Growth inhibitory protein 10)
Gene: SNU114

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.761

The method score is based on:

Property Details
Experiments 19525970, 17934474, 18953335, 16429126, 25670679, 11720284, 10449419, 10377396, 16554755, 16540695, 37968396, 14759368
Identification Methods anti bait coimmunoprecipitation, molecular sieving, pull down, anti tag coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, biochemical
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000388 - spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
GO:0005682 - U5 snRNP
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 2163
Sc

1 1008
+ Hs
+ Dm
+ At
+ Sp
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ Sc
+ Sp

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Last updated: 15 Jul 2024