HitPredict

Interactor 1: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Interactor 2: RPN10 (P38886)
26S proteasome regulatory subunit RPN10
Gene: RPN10

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.971

Property	Details
Experiments	11805826, 17360968, 18757749, 33617881, 20064467, 17978571, 16554755, 37968396, 21619884, 16429126
Identification Methods	tandem affinity purification, pull down, affinity chromatography technology
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	VWA_2~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0031593 - polyubiquitin modification-dependent protein binding GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 398 Sc			1 268
+	At
		874019 RD23B_ARATH (2-398): 1.17e-99: 302: 27.41		PSMD4_ARATH (1-243): 8.44e-117: 341: 45.71
+	At
		874016 RD23D_ARATH (2-398): 1.24e-97: 297: 26.37		PSMD4_ARATH (1-243): 8.44e-117: 341: 45.71
+	At
		874018 RD23A_ARATH (2-398): 7.5e-98: 297: 26.98		PSMD4_ARATH (1-243): 8.44e-117: 341: 45.71
+	Rn
		1117345 RD23B_RAT (2-398): 7.78e-92: 284: 27.50		Q9ESH1_RAT (1-236): 4.25e-119: 347: 49.15
+	Hs
		872242 RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50		PSMD4_HUMAN (1-236): 5.46e-119: 347: 49.15
+	Hs
		872125 RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09		PSMD4_HUMAN (1-236): 5.46e-119: 347: 49.15
+	At
		874017 RD23C_ARATH (2-398): 8.2e-89: 276: 25.62		PSMD4_ARATH (1-243): 8.44e-117: 341: 45.71
+	Zm
		22892 A0A1D6I428_MAIZE (2-398): 1.14e-88: 277: 21.19		A0A1D6KBS7_MAIZE (1-267): 2.53e-114: 334: 40.67
+	Dm
		874035 Q9V3W9_DROME (2-398): 1.44e-82: 260: 24.77		PSMD4_DROME (1-256): 5.75e-113: 332: 41.80
+	Hs
		874198 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PSMD4_HUMAN (1-236): 5.46e-119: 347: 49.15
+	Hs
		874195 UBQL2_HUMAN (1-373): 8.68e-55: 192: 12.65		PSMD4_HUMAN (1-236): 5.46e-119: 347: 49.15
+	Hs
		874185 UBQL4_HUMAN (2-373): 1.16e-52: 186: 13.76		PSMD4_HUMAN (1-236): 5.46e-119: 347: 49.15
+	Dm
		874047 Q9VXF9_DROME (2-397): 3.6e-54: 187: 14.32		PSMD4_DROME (1-256): 5.75e-113: 332: 41.80
+	Xl
		1118797 Q9PVN8_XENLA (1-373): 6.05e-49: 176: 13.33		Q4V845_XENLA (1-236): 2.49e-117: 342: 48.73
+	Dm
		874036 Q9VCD5_DROME (2-398): 1.55e-52: 178: 20.55		PSMD4_DROME (1-256): 5.75e-113: 332: 41.80
+	Hs
		803454 BAG6_HUMAN (2-369): 6.15e-43: 162: 11.96		PSMD4_HUMAN (1-236): 5.46e-119: 347: 49.15
+	Dm
		874046 Q9VWD9_DROME (2-374): 1.81e-47: 171: 13.38		PSMD4_DROME (1-256): 5.75e-113: 332: 41.80
+	Xl
		1118798 BAG6A_XENLA (2-369): 4.33e-42: 160: 14.44		Q4V845_XENLA (1-236): 2.49e-117: 342: 48.73
+	At
		874024 DSK2B_ARATH (4-398): 2.69e-40: 151: 14.61		PSMD4_ARATH (1-243): 8.44e-117: 341: 45.71
+	Ce
		247744 Q23451_CAEEL (1-398): 7.52e-61: 201: 24.13		PSMD4_CAEEL (1-240): 3.05e-92: 277: 39.26