HitPredict

Interactor 1: BRR2 (P32639)
Pre-mRNA-splicing helicase BRR2 (EC 3.6.4.13) (Protein Snu246)
Gene: BRR2

Interactor 2: RUXF (P54999)
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)
Gene: SMX3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.717

Property	Details
Experiments	16554755, 25670679, 10449419, 10377396, 37968396, 16429126
Identification Methods	affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0005682 - U5 snRNP GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2163 Sc			1 86
+	Hs
		272089 U520_HUMAN (16-2163): 0: 1597: 38.84		RUXF_HUMAN (12-84): 3.52e-34: 113: 57.53
+	Sc
		697264 BRR2_YEAST (1-2163): 0: 1534: 100.00		LSM6_YEAST (4-83): 8.53e-21: 80.1: 26.19
+	Sc
		851995 HFM1_YEAST (354-1251): 7.61e-102: 359: 24.46		LSM6_YEAST (4-83): 8.53e-21: 80.1: 26.19
+	Hs
		571387 DDX5_HUMAN (1344-1752): 6.23e-93: 317: 11.35		RUXF_HUMAN (12-84): 3.52e-34: 113: 57.53
+	Sp
		143019 YE02_SCHPO (377-925): 4.47e-87: 311: 21.59		RUXF_SCHPO (9-83): 6.68e-32: 107: 60.00
+	Hs
		911952 DDX23_HUMAN (1275-1768): 3.27e-82: 292: 13.30		RUXF_HUMAN (12-84): 3.52e-34: 113: 57.53
+	Hs
		912250 DDX23_HUMAN (1275-1768): 3.27e-82: 292: 13.30		LSM6_HUMAN (9-83): 1.57e-33: 112: 40.00
+	Sc
		622331 PRP22_YEAST (1343-1825): 7.15e-45: 180: 10.74		RUXF_YEAST (1-86): 1.06e-35: 117: 100.00