HitPredict

Interactor 1: BRR2 (P32639)
Pre-mRNA-splicing helicase BRR2 (EC 3.6.4.13) (Protein Snu246)
Gene: BRR2

Interactor 2: RSE1 (Q04693)
Pre-mRNA-splicing factor RSE1 (RNA splicing and ER to Golgi transport factor 1) (Spliceosome-associated protein 130)
Gene: RSE1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	25670679, 16429126, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005681 - spliceosomal complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 2163 Sc			1 1361
+	Hs
		272151 U520_HUMAN (16-2163): 0: 1597: 38.84		SF3B3_HUMAN (58-1360): 0: 1037: 23.11
+	Sp
		143223 YE02_SCHPO (377-925): 4.47e-87: 311: 21.59		RSE1_SCHPO (57-1359): 0: 894: 22.90
+	Sp
		1350750 PRP11_SCHPO (1279-1804): 1.39e-79: 288: 12.02		RSE1_SCHPO (57-1359): 0: 894: 22.90
+	Sp
		143035 YE02_SCHPO (377-925): 4.47e-87: 311: 21.59		CFT1_SCHPO (48-1356): 0: 677: 12.67