Interactor 1: TFB1 (P32776)
General transcription and DNA repair factor IIH subunit TFB1 (TFIIH subunit TFB1) (RNA polymerase II transcription factor B 73 kDa subunit) (RNA polymerase II transcription factor B p73 subunit) (RNA polymerase II transcription factor B subunit 1)
Gene: TFB1

Interactor 2: RAD25 (Q00578)
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2 (TFIIH subunit XPB/SSL2) (EC 5.6.2.4) (DNA 3'-5' helicase/translocase XPB/SSL2) (DNA repair helicase RAD25/SSL2) (RNA polymerase II transcription factor B subunit SSL2) (TFB subunit SSL2) (Suppressor of stem-loop mutation 2)
Gene: SSL2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.805

The method score is based on:

Property Details
Experiments 37968396, 26340423, 8621533
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ERCC3_RAD25_C~PH_TFIIH
Common GO terms GO:0000112 - nucleotide-excision repair factor 3 complex
GO:0000439 - transcription factor TFIIH core complex
GO:0005634 - nucleus
GO:0005675 - transcription factor TFIIH holo complex
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 642
Sc

1 843
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024