HitPredict

Interactor 1: SLA1 (P32790)
Actin cytoskeleton-regulatory complex protein SLA1
Gene: SLA1

Interactor 2: DEF1 (P35732)
RNA polymerase II degradation factor 1 (RRM3-interacting protein 1)
Gene: DEF1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	29180430, 19841731
Identification Methods	affinity chromatography technology, two hybrid, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043130 - ubiquitin binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1244 Sc			1 738
+	Sc
		698013 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		MDN1_YEAST (34-486): 2.02e-18: 92.9: 12.26
+	Sc
		692215 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		DEF1_YEAST (1-738): 7.77e-65: 231: 100.00
+	Mm
		1351630 PCLO_MOUSE (151-1049): 1.74e-16: 88: 8.79		PCLO_MOUSE (7-674): 1.15e-13: 77.4: 8.39
+	Hs
		1056953 ATX2_HUMAN (520-1240): 1.1e-09: 65.3: 8.02		MDC1_HUMAN (17-690): 1.55e-12: 73.5: 8.61