HitPredict

Interactor 1: SLA1 (P32790)
Actin cytoskeleton-regulatory complex protein SLA1
Gene: SLA1

Interactor 2: ARPC1 (P38328)
Actin-related protein 2/3 complex subunit 1 (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene: ARC40

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.658

Property	Details
Experiments	18467557, 34887356, 37968396
Identification Methods	protein complementation assay, affinity chromatography technology, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030479 - actin cortical patch GO:0043130 - ubiquitin binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1244 Sc			1 384
+	Sc
		697972 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		COPA_YEAST (2-371): 4.32e-26: 112: 8.66
+	Sc
		692223 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		ARPC1_YEAST (1-384): 7.16e-76: 241: 96.62
+	Hs
		1281391 PRR36_HUMAN (123-1052): 1.66e-14: 81.1: 7.35		FBXW7_HUMAN (1-321): 3.45e-66: 224: 11.89
+	Hs
		1057782 NCOA6_HUMAN (128-1210): 2.42e-11: 70.7: 7.02		FBXW7_HUMAN (1-321): 3.45e-66: 224: 11.89
+	Hs
		867085 SC24C_HUMAN (619-982): 3.04e-09: 63.6: 11.41		SEC13_HUMAN (31-313): 1.31e-64: 210: 20.89
+	Hs
		903374 KMT2C_HUMAN (196-1026): 1.34e-13: 78.4: 7.10		WDR5_HUMAN (182-383): 7.51e-36: 135: 12.75
+	Mm
		903669 KMT2C_MOUSE (159-959): 1.72e-11: 71.5: 7.25		WDR5_MOUSE (182-383): 7.51e-36: 135: 12.75
+	Hs
		903229 NCOA6_HUMAN (128-1210): 2.42e-11: 70.7: 7.02		WDR5_HUMAN (182-383): 7.51e-36: 135: 12.75
+	Hs
		903345 Q86V38_HUMAN (649-1244): 2.59e-09: 64.1: 7.89		WDR5_HUMAN (182-383): 7.51e-36: 135: 12.75
+	Hs
		929629 ATX2_HUMAN (520-1240): 1.1e-09: 65.3: 8.02		RACK1_HUMAN (1-141): 2.31e-20: 92.5: 12.93
+	Sc
		758551 SEC31_YEAST (838-1241): 1.08e-11: 71.7: 7.56		SEC13_YEAST (19-190): 1.7e-09: 60.3: 13.33