HitPredict

Interactor 1: B1AXJ3 (B1AXJ3)
Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Gene: Lrp8

Interactor 2: JIP2 (Q9ERE9)
C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2)
Gene: Mapk8ip2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.50	0.535

Property	Details
Experiments	20923933, 10827199
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 832 Mm			1 830
+	Mm
		1266181 LRP8_MOUSE (8-832): 0: 704: 83.22		JIP2_MOUSE (1-830): 1.18e-174: 526: 100.00
+	Mm
		69888 B1AXJ3_MOUSE (19-832): 0: 813: 100.00		JIP1_MOUSE (13-349): 1.11e-15: 83.3: 22.35
+	Mm
		1266182 LRP8_MOUSE (8-832): 0: 704: 83.22		JIP1_MOUSE (13-349): 1.11e-15: 83.3: 22.35
+	Mm
		57562 LRP2_MOUSE (120-327): 1.15e-09: 64.4: 15.79		JIP2_MOUSE (1-830): 1.18e-174: 526: 100.00
+	Mm
		1322325 LRP1B_MOUSE (7-148): 2.23e-09: 63.6: 14.74		JIP2_MOUSE (1-830): 1.18e-174: 526: 100.00
+	Hs
		1032902 LRP8_HUMAN (4-194): 2.03e-22: 105: 23.30		JIP2_HUMAN (1-830): 5.03e-144: 446: 84.51
+	Hs
		957599 LRP2_HUMAN (119-313): 1.46e-10: 67.5: 12.67		JIP2_HUMAN (1-830): 5.03e-144: 446: 84.51
+	Hs
		992661 LRP1_HUMAN (7-148): 1.04e-09: 64.8: 16.88		JIP2_HUMAN (1-830): 5.03e-144: 446: 84.51
+	Hs
		992719 LRP1_HUMAN (7-148): 1.04e-09: 64.8: 16.88		GULP1_HUMAN (689-820): 5.03e-42: 157: 27.82
+	Hs
		957612 LRP2_HUMAN (119-313): 1.46e-10: 67.5: 12.67		ARH_HUMAN (689-815): 4.27e-39: 149: 20.16
+	Hs
		957621 LRP2_HUMAN (119-313): 1.46e-10: 67.5: 12.67		ANS1B_HUMAN (563-815): 1.75e-35: 147: 18.99
+	Hs
		992682 LRP1_HUMAN (7-148): 1.04e-09: 64.8: 16.88		ANS1B_HUMAN (563-815): 1.75e-35: 147: 18.99
+	Mm
		57558 LRP2_MOUSE (120-327): 1.15e-09: 64.4: 15.79		ARH_MOUSE (673-815): 3.15e-37: 144: 18.62
+	Mm
		1257662 LRP4_MOUSE (68-331): 3.55e-27: 121: 23.63		JIP1_MOUSE (13-349): 1.11e-15: 83.3: 22.35
+	Rn
		88518 LRP2_RAT (120-341): 7.54e-10: 65.2: 13.93		ARH_RAT (673-815): 7.93e-35: 136: 18.62
+	Hs
		1048463 LRP8_HUMAN (4-194): 2.03e-22: 105: 23.30		JIP1_HUMAN (13-349): 1.7e-13: 76.3: 22.73
+	Mm
		57563 LRP2_MOUSE (120-327): 1.15e-09: 64.4: 15.79		JIP1_MOUSE (13-349): 1.11e-15: 83.3: 22.35
+	Mm
		1337450 LRP1B_MOUSE (7-148): 2.23e-09: 63.6: 14.74		JIP1_MOUSE (13-349): 1.11e-15: 83.3: 22.35
+	Hs
		957662 LRP2_HUMAN (119-313): 1.46e-10: 67.5: 12.67		JIP1_HUMAN (13-349): 1.7e-13: 76.3: 22.73
+	Hs
		992729 LRP1_HUMAN (7-148): 1.04e-09: 64.8: 16.88		JIP1_HUMAN (13-349): 1.7e-13: 76.3: 22.73