HitPredict

Interactor 1: GSP1 (P32835)
GTP-binding nuclear protein GSP1/CNR1 (Chromosome stability protein 17) (GTPase Ran homolog) (Genetic suppressor of PRP20-1)
Gene: GSP1

Interactor 2: MSN5 (P52918)
Protein MSN5
Gene: MSN5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.925

Property	Details
Experiments	9214382, 25838545, 19812255, 18719252, 21329658
Identification Methods	affinity chromatography technology, pull down, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Exportin-5~Ras
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 219 Sc			1 1224
+	Hs
		914368 RB11A_HUMAN (1-207): 4.63e-79: 237: 26.17		XPO5_HUMAN (1-1049): 0: 786: 18.66
+	Hs
		919273 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		XPO5_HUMAN (1-1049): 0: 786: 18.66
+	At
		784985 RAN1_ARATH (1-216): 6.84e-94: 275: 75.58		HASTY_ARATH (1-1043): 0: 610: 16.80
+	Sc
		675912 GSP1_YEAST (1-219): 1.49e-79: 239: 100.00		XPO1_YEAST (2-935): 0: 590: 11.12
+	Hs
		162599 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		XPO1_HUMAN (2-935): 7.21e-169: 531: 10.43
+	At
		784987 RAN1_ARATH (1-216): 6.84e-94: 275: 75.58		MOS14_ARATH (1-959): 4.04e-94: 326: 11.03
+	Hs
		207921 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		XPOT_HUMAN (17-688): 4.12e-100: 343: 11.69
+	Hs
		919228 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		XPO6_HUMAN (2-675): 1.36e-92: 324: 11.76
+	Hs
		297168 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		IPO13_HUMAN (3-712): 9.98e-75: 270: 11.92
+	Sc
		698755 GSP1_YEAST (1-219): 1.49e-79: 239: 100.00		XPOT_YEAST (6-654): 2.02e-70: 259: 11.27
+	Sc
		699000 GSP2_YEAST (1-219): 9.33e-78: 234: 96.82		XPOT_YEAST (6-654): 2.02e-70: 259: 11.27
+	Sc
		698996 GSP1_YEAST (1-219): 1.49e-79: 239: 100.00		MTR10_YEAST (1-651): 5.59e-68: 250: 14.18
+	Sc
		699022 GSP2_YEAST (1-219): 9.33e-78: 234: 96.82		MTR10_YEAST (1-651): 5.59e-68: 250: 14.18
+	Sp
		292805 SPI1_SCHPO (5-219): 6.33e-77: 232: 88.37		XPOT_SCHPO (4-709): 2.51e-68: 251: 10.40
+	Hs
		207913 RAB9A_HUMAN (8-170): 8.21e-28: 106: 31.77		XPOT_HUMAN (17-688): 4.12e-100: 343: 11.69
+	Hs
		919301 RAN_HUMAN (1-216): 3.71e-76: 230: 80.56		XPO7_HUMAN (2-458): 6.53e-17: 88.8: 9.87
+	Sc
		697582 GSP1_YEAST (1-219): 1.49e-79: 239: 100.00		KA122_YEAST (4-806): 2.22e-09: 64.2: 11.03
+	Sc
		697583 GSP2_YEAST (1-219): 9.33e-78: 234: 96.82		KA122_YEAST (4-806): 2.22e-09: 64.2: 11.03