HitPredict

Interactor 1: THOC2 (B1AZI6)
THO complex subunit 2 (Tho2)
Gene: THOC2

Interactor 2: EED (Q921E6)
Polycomb protein EED
Gene: EED

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Thoc2~WD40, THOC2_N~WD40
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1594 Mm			1 441
+	Hs
		268185 THOC2_HUMAN (11-1594): 0: 1716: 97.41		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		1246350 THOC2_HUMAN (11-1594): 0: 1716: 97.41		THOC3_HUMAN (148-434): 3.97e-16: 81.3: 19.03
+	Mm
		1154100 NIPBL_MOUSE (1135-1587): 1.32e-34: 147: 15.43		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		268306 SLTM_HUMAN (1137-1592): 6.36e-27: 121: 9.96		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1208465 SLTM_MOUSE (1133-1591): 2.42e-26: 119: 9.91		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		268143 NIPBL_HUMAN (1149-1574): 2.15e-23: 111: 12.69		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		268136 ZC3HD_HUMAN (1142-1593): 2.56e-20: 100: 13.59		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		268083 EIF3A_HUMAN (1075-1594): 1.22e-18: 95: 10.89		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		268238 MINT_HUMAN (1127-1552): 2.68e-17: 91.1: 14.87		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		268151 RBBP6_HUMAN (1151-1593): 2.1e-13: 78: 13.97		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		612549 EIF3A_MOUSE (1098-1557): 6.03e-13: 76.5: 10.35		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		1281340 SCAFB_HUMAN (1127-1594): 4.39e-33: 142: 12.06		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1288263 SCAFB_HUMAN (1127-1594): 4.39e-33: 142: 12.06		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		1132721 ZC3HD_HUMAN (1142-1593): 2.56e-20: 100: 13.59		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		1288258 MINT_HUMAN (1127-1552): 2.68e-17: 91.1: 14.87		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		1132750 ZC3HD_HUMAN (1142-1593): 2.56e-20: 100: 13.59		NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09
+	Hs
		1302927 MINT_HUMAN (1127-1552): 2.68e-17: 91.1: 14.87		NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09
+	Hs
		1191704 RBBP6_HUMAN (1151-1593): 2.1e-13: 78: 13.97		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		903218 EIF3A_HUMAN (1075-1594): 1.22e-18: 95: 10.89		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		1191731 RBBP6_HUMAN (1151-1593): 2.1e-13: 78: 13.97		NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09