HitPredict

Interactor 1: STX1A (P32850)
Syntaxin-1A (Neuron-specific antigen HPC-1) (Synaptotagmin-associated 35 kDa protein) (P35A)
Gene: STX1A

Interactor 2: STXB1 (P61763)
Syntaxin-binding protein 1 (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67)
Gene: STXBP1

Species: Bos taurus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.690

Property	Details
Experiments	17363971
Identification Methods	pull down, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SNARE~Sec1, Sec1~Syntaxin
Common GO terms	GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 288 Bt			1 594
+	Mm
		139528 STX1A_MOUSE (1-288): 5.69e-85: 258: 97.57		STXB1_MOUSE (1-594): 0: 680: 100.00
+	Rn
		699173 STX1A_RAT (1-288): 7.08e-85: 257: 97.92		STXB1_RAT (1-594): 0: 680: 100.00
+	Mm
		139543 STX1B_MOUSE (1-288): 5.36e-84: 255: 84.38		STXB1_MOUSE (1-594): 0: 680: 100.00
+	Rn
		898824 STX1B_RAT (1-288): 5.36e-84: 255: 84.38		STXB1_RAT (1-594): 0: 680: 100.00
+	Hs
		898829 STX1B_HUMAN (1-288): 5.36e-84: 255: 84.38		STXB1_HUMAN (1-594): 0: 680: 100.00
+	Hs
		901790 STX1A_HUMAN (1-287): 3.96e-83: 253: 97.91		STXB1_HUMAN (1-594): 0: 680: 100.00
+	Hs
		699253 STX2_HUMAN (1-288): 3.79e-80: 245: 63.89		STXB1_HUMAN (1-594): 0: 680: 100.00
+	Mm
		192851 STX1A_MOUSE (1-288): 5.69e-85: 258: 97.57		STXB2_MOUSE (1-593): 0: 659: 62.80
+	Rn
		838509 STX2_RAT (1-266): 1.12e-73: 229: 65.92		STXB1_RAT (1-594): 0: 680: 100.00
+	Rn
		699178 STX1A_RAT (1-288): 7.08e-85: 257: 97.92		STXB2_RAT (1-593): 0: 647: 62.35
+	Hs
		699262 STX2_HUMAN (1-288): 3.79e-80: 245: 63.89		STXB2_HUMAN (1-593): 0: 658: 63.47
+	Hs
		901776 STX4_HUMAN (1-284): 1.61e-63: 203: 44.03		STXB1_HUMAN (1-594): 0: 680: 100.00
+	Rn
		838510 STX2_RAT (1-266): 1.12e-73: 229: 65.92		STXB2_RAT (1-593): 0: 647: 62.35
+	Dm
		991124 STX1A_DROME (2-287): 3.07e-75: 233: 68.40		ROP_DROME (4-589): 0: 623: 62.67
+	Ce
		183451 STX1A_CAEEL (2-283): 2.41e-73: 228: 63.25		UNC18_CAEEL (4-590): 0: 603: 58.11
+	Hs
		119613 STX2_HUMAN (1-288): 3.79e-80: 245: 63.89		STXB3_HUMAN (1-593): 0: 584: 50.59
+	Hs
		119633 STX4_HUMAN (1-284): 1.61e-63: 203: 44.03		STXB3_HUMAN (1-593): 0: 584: 50.59
+	Hs
		1017732 STX4_HUMAN (1-284): 1.61e-63: 203: 44.03		SCFD1_HUMAN (4-588): 8.01e-163: 481: 14.62
+	Dm
		1096639 STX1A_DROME (2-287): 3.07e-75: 233: 68.40		SLY1_DROME (5-586): 5.16e-142: 427: 13.77
+	Hs
		1017818 STX4_HUMAN (1-284): 1.61e-63: 203: 44.03		VPS45_HUMAN (12-582): 5.03e-154: 456: 17.81