HitPredict

Interactor 1: IL1R2 (P27930)
Interleukin-1 receptor type 2 (IL-1R-2) (IL-1RT-2) (IL-1RT2) (CD121 antigen-like family member B) (CDw121b) (IL-1 type II receptor) (Interleukin-1 receptor beta) (IL-1R-beta) (Interleukin-1 receptor type II) (CD antigen CD121b) [Cleaved into: Interleukin-1 receptor type 2, membrane form (mIL-1R2) (mIL-1RII); Interleukin-1 receptor type 2, soluble form (sIL-1R2) (sIL-1RII)]
Gene: IL1R2

Interactor 2: SAR1B (Q9Y6B6)
Small COPII coat GTPase SAR1B (EC 3.6.5.2) (GTP-binding protein B) (GTBPB) (Secretion-associated Ras-related GTPase 1B)
Gene: SAR1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 398 Hs			1 198
+	Hs
		612139 FGFR3_HUMAN (7-383): 2.89e-58: 205: 16.75		ARF4_HUMAN (10-197): 8.67e-74: 221: 27.66
+	Hs
		650436 FGFR3_HUMAN (7-383): 2.89e-58: 205: 16.75		SAR1A_HUMAN (1-198): 5.13e-63: 195: 89.90
+	Hs
		975357 ROBO1_HUMAN (5-355): 3.39e-20: 95: 10.53		ARF6_HUMAN (21-196): 1.2e-73: 221: 30.11
+	Hs
		1491827 ROBO1_HUMAN (5-355): 3.39e-20: 95: 10.53		SAR1B_HUMAN (1-198): 3.43e-64: 198: 100.00
+	Hs
		975152 TITIN_HUMAN (109-362): 2.01e-09: 61.9: 10.16		ARF6_HUMAN (21-196): 1.2e-73: 221: 30.11
+	Hs
		1249997 LRIG3_HUMAN (42-242): 9.15e-15: 78.3: 22.66		SAR1B_HUMAN (1-198): 3.43e-64: 198: 100.00
+	Hs
		1249986 LRIG3_HUMAN (42-242): 9.15e-15: 78.3: 22.66		SAR1A_HUMAN (1-198): 5.13e-63: 195: 89.90
+	Hs
		1361950 TITIN_HUMAN (109-362): 2.01e-09: 61.9: 10.16		SAR1B_HUMAN (1-198): 3.43e-64: 198: 100.00
+	Hs
		1326529 ROBO1_HUMAN (5-355): 3.39e-20: 95: 10.53		ARL14_HUMAN (24-197): 1.44e-25: 99.4: 32.00