Protein: ROBO1
Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1)

Gene: ROBO1
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q9Y6N7

Gene Ontology (top 5):
GO:0002042 - cell migration involved in sprouting angiogenesis
GO:0003129 - heart induction
GO:0003148 - outflow tract septum morphogenesis
GO:0003180 - aortic valve morphogenesis
GO:0003184 - pulmonary valve morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1462071

CLC4A
C-type lectin domain family 4 member A

2

4

High-throughput

0.776

High

376163

RASK
GTPase KRas

2

11

High-throughput

0.754

High

978442

RHOB
Rho-related GTP-binding protein RhoB

2

12

High-throughput

0.754

High

249220

DSCAM
Cell adhesion molecule DSCAM

1

16

High-throughput

0.698

High

317597

SLIT2
Slit homolog 2 protein

1

15

Small-scale

0.692

High

164877

SH21B
SH2 domain-containing protein 1B

1

8

High-throughput

0.691

High

596553

CTLA4
Cytotoxic T-lymphocyte protein 4

1

3

High-throughput

0.691

High

858739

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

1

High-throughput

0.691

High

1418685

PAR6B
Partitioning defective 6 homolog beta

1

1

High-throughput

0.691

High

1353443

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

4

4

Small-scale

0.683

High

668098

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.656

High

821696

TPOR
Thrombopoietin receptor

1

0

High-throughput

0.656

High

1355954

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

3

0

High-throughput

0.634

High

1108777

TBB3
Tubulin beta-3 chain

1

1

High-throughput

0.621

High

1158215

MK14
Mitogen-activated protein kinase 14

1

5

High-throughput

0.621

High

374318

RASN
GTPase NRas

1

11

High-throughput

0.618

High

375059

RASH
GTPase HRas

1

10

High-throughput

0.618

High

463875

LYN
Tyrosine-protein kinase Lyn

1

6

High-throughput

0.618

High

466555

RHOC
Rho-related GTP-binding protein RhoC

1

10

High-throughput

0.618

High

601524

RHOQ
Rho-related GTP-binding protein RhoQ

1

14

High-throughput

0.618

High

631604

RAB5A
Ras-related protein Rab-5A

1

4

High-throughput

0.618

High

648757

FGFR4
Fibroblast growth factor receptor 4

1

9

High-throughput

0.618

High

710600

EPHA2
Ephrin type-A receptor 2

1

7

High-throughput

0.618

High

845884

MUC18
Cell surface glycoprotein MUC18

1

19

High-throughput

0.618

High

891378

GSK3A
Glycogen synthase kinase-3 alpha

1

3

High-throughput

0.618

High

891928

GSK3B
Glycogen synthase kinase-3 beta

1

4

High-throughput

0.618

High

910279

RND2
Rho-related GTP-binding protein RhoN

1

14

High-throughput

0.618

High

955810

CDC42
Cell division control protein 42 homolog

1

11

High-throughput

0.618

High

962694

RHOA
Transforming protein RhoA

1

10

High-throughput

0.618

High

962874

RND3
Rho-related GTP-binding protein RhoE

1

13

High-throughput

0.618

High

976711

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.618

High

988870

RAC1
Ras-related C3 botulinum toxin substrate 1

1

9

High-throughput

0.618

High

1145208

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.618

High

1151957

RHOH
Rho-related GTP-binding protein RhoH

1

14

High-throughput

0.618

High

1256324

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.618

High

1271077

RHOU
Rho-related GTP-binding protein RhoU

1

15

High-throughput

0.618

High

1362045

ROBO4
Roundabout homolog 4

1

19

Small-scale

0.618

High

1366928

RND1
Rho-related GTP-binding protein Rho6

1

13

High-throughput

0.618

High

1396673

RHOV
Rho-related GTP-binding protein RhoV

1

11

High-throughput

0.618

High

1433609

RHOJ
Rho-related GTP-binding protein RhoJ

1

14

High-throughput

0.618

High

1439198

ROBO2
Roundabout homolog 2

1

17

Small-scale

0.618

High

1462024

ALK
ALK tyrosine kinase receptor

1

7

High-throughput

0.618

High

1491858

ROBO1
Roundabout homolog 1

1

16

Small-scale

0.618

High

1407321

CML1
Chemerin-like receptor 1

2

2

High-throughput

0.601

High

1437662

PELI2
E3 ubiquitin-protein ligase pellino homolog 2

2

0

Small-scale

0.593

High

408203

TBB4A
Tubulin beta-4A chain

1

1

High-throughput

0.590

High

247479

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

0

High-throughput

0.586

High

1227806

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.586

High

188106

MOT6
Monocarboxylate transporter 6

1

5

High-throughput

0.575

High

1274109

MOT9
Monocarboxylate transporter 9

1

3

High-throughput

0.575

High

212793

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

2

4

High-throughput

0.571

High

1279854

SRGP1
SLIT-ROBO Rho GTPase-activating protein 1

2

4

High-throughput

0.571

High

269641

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

4

Small-scale

0.536

High

1460887

FBX2
F-box only protein 2

1

6

High-throughput

0.536

High

1491844

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

1

High-throughput

0.536

High

1219565

ANR22
Ankyrin repeat domain-containing protein 22

1

1

High-throughput

0.514

High

1491852

TEST
Testisin

1

0

High-throughput

0.513

High

1022836

RHG04
Rho GTPase-activating protein 4

1

4

Small-scale

0.501

High

601926

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.493

High

189964

STX7
Syntaxin-7

1

4

High-throughput

0.479

High

219042

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

604301

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

715873

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

941865

ARL4C
ADP-ribosylation factor-like protein 4C

1

7

High-throughput

0.479

High

1041400

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

1087360

STX4
Syntaxin-4

1

4

High-throughput

0.479

High

1159932

OCLN
Occludin

1

2

High-throughput

0.479

High

1258331

MOB2
MOB kinase activator 2

1

3

High-throughput

0.479

High

1258435

MOB3C
MOB kinase activator 3C

1

3

High-throughput

0.479

High

1273140

MOB1B
MOB kinase activator 1B

1

3

High-throughput

0.479

High

1323068

CXD3
Gap junction delta-3 protein

1

5

High-throughput

0.479

High

1326529

ARL14
ADP-ribosylation factor-like protein 14

1

3

High-throughput

0.479

High

1400361

FMNL2
Formin-like protein 2

1

1

High-throughput

0.479

High

1433028

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.479

High

1436466

MOB1A
MOB kinase activator 1A

1

3

High-throughput

0.479

High

1459510

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1491827

SAR1B
Small COPII coat GTPase SAR1B

1

4

High-throughput

0.479

High

226290

STX6
Syntaxin-6

1

0

High-throughput

0.458

High

643172

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.458

High

975357

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

1108338

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1233627

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1429901

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

1435525

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

388475

B3AT
Band 3 anion transport protein

1

1

High-throughput

0.445

High

480944

LEG1
Galectin-1

1

11

High-throughput

0.445

High

530685

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.445

High

641994

CD9
CD9 antigen

1

5

High-throughput

0.445

High

722890

SSR2
Somatostatin receptor type 2

1

6

High-throughput

0.445

High

914517

EFNB2
Ephrin-B2

1

1

High-throughput

0.445

High

948980

CD81
CD81 antigen

1

5

High-throughput

0.445

High

1119412

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

5

High-throughput

0.445

High

1323795

S39AB
Zinc transporter ZIP11

1

2

High-throughput

0.445

High

1357240

BRK1
Protein BRICK1

1

1

Small-scale

0.445

High

1461797

FZD10
Frizzled-10

1

1

High-throughput

0.445

High

1330712

MAGB6
Melanoma-associated antigen B6

1

2

High-throughput

0.439

High

140049

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

327525

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

1454882

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.437

High

844909

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.426

High

1010992

BAT1
b(0,+)-type amino acid transporter 1

1

0

High-throughput

0.426

High

1106186

TUSC3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3

1

0

High-throughput

0.426

High

1168768

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.426

High

1390910

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.426

High

1420300

S13A1
Solute carrier family 13 member 1

1

0

High-throughput

0.426

High

171044

CLGN
Calmegin

1

5

High-throughput

0.407

High

1231985

IL31
Interleukin-31

1

0

High-throughput

0.279

Low

181749

CTDSL
CTD small phosphatase-like protein

1

0

High-throughput

0.249

Low

1382026

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

418551

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.232

Low

1389645

SAAL1
Protein SAAL1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025