HitPredict

Interactor 1: A8MQ02 (A8MQ02)
Afadin (Afadin adherens junction formation factor)
Gene: AFDN

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1781 Hs			1 247
+	Hs
		70024 A8MQ02_HUMAN (1-1781): 0: 1190: 100.00		1433E_HUMAN (1-244): 2.03e-141: 398: 63.53
+	Hs
		936286 AFAD_HUMAN (1-1781): 0: 1179: 99.78		1433E_HUMAN (1-244): 2.03e-141: 398: 63.53
+	Hs
		936284 AFAD_HUMAN (1-1781): 0: 1179: 99.78		1433G_HUMAN (1-247): 3.17e-139: 392: 100.00
+	Hs
		936309 AFAD_HUMAN (1-1781): 0: 1179: 99.78		1433F_HUMAN (1-246): 2.51e-135: 382: 86.99
+	Hs
		70025 A8MQ02_HUMAN (1-1781): 0: 1190: 100.00		1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59
+	Hs
		729702 AFAD_HUMAN (1-1781): 0: 1179: 99.78		1433B_HUMAN (2-247): 1.92e-109: 317: 75.40
+	Hs
		936291 AFAD_HUMAN (1-1781): 0: 1179: 99.78		1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59
+	Hs
		690857 AFAD_HUMAN (1-1781): 0: 1179: 99.78		1433T_HUMAN (2-245): 5.55e-105: 305: 70.33
+	Hs
		114463 H0Y8L4_HUMAN (1470-1781): 1.63e-84: 281: 100.00		1433F_HUMAN (1-246): 2.51e-135: 382: 86.99
+	Hs
		114462 H0Y8L4_HUMAN (1470-1781): 1.63e-84: 281: 100.00		1433B_HUMAN (2-247): 1.92e-109: 317: 75.40
+	Hs
		245908 KIF1B_HUMAN (205-548): 4.32e-45: 182: 16.76		1433E_HUMAN (1-244): 2.03e-141: 398: 63.53
+	Hs
		245906 KIF1B_HUMAN (205-548): 4.32e-45: 182: 16.76		1433G_HUMAN (1-247): 3.17e-139: 392: 100.00
+	Hs
		245919 KIF1B_HUMAN (205-548): 4.32e-45: 182: 16.76		1433F_HUMAN (1-246): 2.51e-135: 382: 86.99
+	Hs
		971881 RADIL_HUMAN (789-1065): 1.68e-28: 127: 17.36		1433E_HUMAN (1-244): 2.03e-141: 398: 63.53
+	Hs
		966747 RADIL_HUMAN (789-1065): 1.68e-28: 127: 17.36		1433G_HUMAN (1-247): 3.17e-139: 392: 100.00
+	Hs
		245876 KIF1B_HUMAN (205-548): 4.32e-45: 182: 16.76		1433B_HUMAN (2-247): 1.92e-109: 317: 75.40
+	Hs
		245909 KIF1B_HUMAN (205-548): 4.32e-45: 182: 16.76		1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59
+	Hs
		245872 KIF1B_HUMAN (205-548): 4.32e-45: 182: 16.76		1433T_HUMAN (2-245): 5.55e-105: 305: 70.33
+	Hs
		245877 KIF1B_HUMAN (205-548): 4.32e-45: 182: 16.76		1433S_HUMAN (2-245): 1.87e-98: 289: 65.16
+	Hs
		730146 RADIL_HUMAN (789-1065): 1.68e-28: 127: 17.36		1433B_HUMAN (2-247): 1.92e-109: 317: 75.40