HitPredict

Interactor 1: YPT7 (P32939)
Ypt/Rab-type GTPase YPT7 (Ypt7p) (Vacuolar morphology protein 4)
Gene: YPT7

Interactor 2: GYP7 (P48365)
GTPase-activating protein GYP7 (GAP for YPT7)
Gene: GYP7

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	16855591
Identification Methods	gtpase assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0005829 - cytosol GO:0016192 - vesicle-mediated transport GO:0032889 - regulation of vacuole fusion, non-autophagic
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 208 Sc			1 746
+	Hs
		845097 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		TBC15_HUMAN (3-699): 2.04e-152: 461: 24.36
+	Hs
		894778 RAB8A_HUMAN (1-206): 1.75e-80: 240: 36.23		TBC15_HUMAN (3-699): 2.04e-152: 461: 24.36
+	Os
		1130874 Q7XHP7_ORYSJ (4-208): 2.9e-74: 225: 36.84		Q5SMT0_ORYSJ (4-690): 9.5e-149: 451: 23.89
+	Os
		1130875 Q84TA8_ORYSJ (4-207): 9.85e-74: 223: 36.06		Q5SMT0_ORYSJ (4-690): 9.5e-149: 451: 23.89
+	Hs
		894747 RAB8A_HUMAN (1-206): 1.75e-80: 240: 36.23		TBC9B_HUMAN (149-746): 1.39e-88: 305: 12.77
+	Hs
		894809 RAB8A_HUMAN (1-206): 1.75e-80: 240: 36.23		TBC17_HUMAN (3-726): 1.22e-90: 299: 20.03
+	Hs
		918951 RAB1A_HUMAN (1-207): 3.26e-79: 237: 36.36		TBC17_HUMAN (3-726): 1.22e-90: 299: 20.03
+	Hs
		845109 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		TB22A_HUMAN (211-700): 9.81e-81: 268: 16.54
+	Hs
		845373 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		RBGP1_HUMAN (169-745): 1.06e-75: 266: 13.56
+	Hs
		894727 RAB8A_HUMAN (1-206): 1.75e-80: 240: 36.23		TBC8B_HUMAN (122-746): 4e-79: 276: 14.80
+	Hs
		914176 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		TBCD1_HUMAN (174-742): 3.29e-79: 277: 14.31
+	Hs
		321281 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		TBCD8_HUMAN (149-746): 4.89e-75: 265: 12.77
+	Hs
		914423 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		TBC14_HUMAN (199-711): 3.07e-74: 256: 16.19
+	Hs
		234370 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		EVI5_HUMAN (230-743): 2.26e-72: 253: 13.12
+	Hs
		233036 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		TBC12_HUMAN (238-718): 2.68e-72: 252: 14.34
+	Hs
		914465 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		TBD2B_HUMAN (271-707): 1.03e-70: 251: 16.04
+	Hs
		914275 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		EVI5L_HUMAN (276-744): 1.78e-69: 245: 13.15
+	Hs
		914391 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		TB22B_HUMAN (278-700): 1.47e-71: 244: 17.69
+	Sc
		701816 YPT7_YEAST (1-208): 1.11e-78: 235: 100.00		GYP1_YEAST (316-632): 4.94e-31: 131: 17.97
+	Sc
		350927 YPT1_YEAST (1-207): 2.19e-73: 222: 32.39		GYP1_YEAST (316-632): 4.94e-31: 131: 17.97