HitPredict

Interactor 1: SWE1 (P32944)
Mitosis inhibitor protein kinase SWE1 (EC 2.7.11.1) (Wee1 homolog)
Gene: SWE1

Interactor 2: KEL1 (P38853)
Kelch repeat-containing protein 1
Gene: KEL1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	11805837, 20489023
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005935 - cellular bud neck
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 819 Sc			1 1164
+	Sc
		409641 KAPC_YEAST (362-729): 3.99e-89: 288: 20.32		KEL1_YEAST (1-1164): 0: 580: 100.00
+	Hs
		682058 AKT1_HUMAN (294-786): 1.04e-140: 426: 14.43		KLHL3_HUMAN (21-410): 1.13e-78: 272: 15.82
+	Sc
		701902 SWE1_YEAST (1-819): 0: 628: 100.00		KEL2_YEAST (902-1154): 3.03e-10: 66.9: 11.87
+	Hs
		568818 KAPCA_HUMAN (429-762): 6.83e-124: 378: 19.29		KLHL3_HUMAN (21-410): 1.13e-78: 272: 15.82
+	Hs
		969079 KPCE_HUMAN (355-790): 1.31e-125: 395: 14.16		KEAP1_HUMAN (250-496): 1.05e-30: 131: 14.34
+	Hs
		784007 KPCI_HUMAN (381-793): 3.43e-125: 390: 18.50		KEAP1_HUMAN (250-496): 1.05e-30: 131: 14.34
+	Hs
		983831 KPCZ_HUMAN (381-795): 3.61e-120: 376: 15.85		KEAP1_HUMAN (250-496): 1.05e-30: 131: 14.34
+	Hs
		1026251 PAK1_HUMAN (339-707): 1.01e-84: 281: 21.62		KLH20_HUMAN (250-487): 1.63e-38: 155: 14.64
+	Hs
		1026157 PAK1_HUMAN (339-707): 1.01e-84: 281: 21.62		KEAP1_HUMAN (250-496): 1.05e-30: 131: 14.34
+	Hs
		1026255 PAK1_HUMAN (339-707): 1.01e-84: 281: 21.62		NS1BP_HUMAN (11-171): 2.91e-11: 69.6: 10.43