Interactor 1: C2TA (P33076)
MHC class II transactivator (CIITA) (EC 2.3.1.-) (EC 2.7.11.1)
Gene: CIITA

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 12697811
Identification Methods pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0045892 - negative regulation of DNA-templated transcription
GO:0045893 - positive regulation of DNA-templated transcription
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1130
Hs

1 482
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024