HitPredict

Interactor 1: KINH (P33176)
Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC)
Gene: KIF5B

Interactor 2: TRAK1 (Q9UPV9)
Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein) (Protein Milton)
Gene: TRAK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	26496610, 24995978
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0047496 - vesicle transport along microtubule GO:0048471 - perinuclear region of cytoplasm GO:1904115 - axon cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 963 Hs			1 953
+	Hs
		230487 KINH_HUMAN (1-963): 5.26e-144: 455: 100.00		TRAK2_HUMAN (30-938): 5.22e-98: 330: 47.15
+	Hs
		1017567 KIF5A_HUMAN (599-962): 8.85e-14: 77.9: 11.72		TRAK1_HUMAN (1-953): 0: 646: 100.00
+	Hs
		229896 KIF5C_HUMAN (658-961): 7.72e-11: 68.3: 12.62		TRAK1_HUMAN (1-953): 0: 646: 100.00
+	Hs
		230481 KIF1B_HUMAN (4-836): 4.2e-112: 382: 23.49		TRAK2_HUMAN (30-938): 5.22e-98: 330: 47.15
+	Hs
		148562 KIF11_HUMAN (8-877): 3.01e-160: 500: 26.43		CTRO_HUMAN (33-527): 4.9e-19: 95.4: 11.83
+	Hs
		702999 KINH_HUMAN (1-963): 5.26e-144: 455: 100.00		MYO5A_HUMAN (47-567): 2.47e-18: 93.1: 11.22
+	Hs
		87354 KINH_HUMAN (1-963): 5.26e-144: 455: 100.00		C9JC32_HUMAN (17-258): 3.88e-10: 66: 10.66
+	Hs
		725033 KI13B_HUMAN (4-760): 3.86e-116: 394: 23.32		MYH9_HUMAN (195-661): 7.37e-17: 88.3: 10.53
+	Hs
		230500 KIF5A_HUMAN (599-962): 8.85e-14: 77.9: 11.72		TRAK2_HUMAN (30-938): 5.22e-98: 330: 47.15
+	Hs
		229823 KIF5C_HUMAN (658-961): 7.72e-11: 68.3: 12.62		TRAK2_HUMAN (30-938): 5.22e-98: 330: 47.15
+	Rn
		1163333 KIF5A_RAT (593-962): 3.76e-13: 76: 11.26		TRAK2_RAT (30-938): 1.34e-94: 321: 45.91
+	Rn
		1102446 KINH_RAT (680-963): 2.5e-11: 69.8: 9.27		TRAK2_RAT (30-938): 1.34e-94: 321: 45.91
+	Rn
		869352 KINH_RAT (680-963): 2.5e-11: 69.8: 9.27		HAP1_RAT (91-524): 3.53e-28: 123: 23.20
+	Rn
		869341 KIF5C_RAT (659-962): 3.56e-11: 69.4: 12.34		HAP1_RAT (91-524): 3.53e-28: 123: 23.20
+	Mm
		193275 KIF5A_MOUSE (575-960): 4.34e-11: 69.1: 8.11		HAP1_MOUSE (91-524): 2.23e-27: 120: 23.80
+	Hs
		253264 KI21A_HUMAN (591-962): 8.18e-12: 71.8: 8.21		KI21B_HUMAN (22-544): 4.05e-14: 79.1: 8.35
+	Dm
		566098 KINH_DROME (575-961): 2.46e-10: 66.7: 9.90		MILT_DROME (258-522): 2.53e-09: 63.3: 10.94