HitPredict

Interactor 1: MRT4 (P33201)
Ribosome assembly factor MRT4 (mRNA turnover protein 4)
Gene: MRT4

Interactor 2: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	16429126, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 236 Sc			1 291
+	Sc
		399650 RLA0_YEAST (20-236): 8.39e-66: 208: 23.87		BRX1_YEAST (1-291): 1.12e-99: 295: 100.00
+	Hs
		401008 RLA0_HUMAN (22-236): 2.82e-74: 229: 24.55		BRX1_HUMAN (26-286): 1.92e-85: 261: 47.91
+	Sc
		703034 MRT4_YEAST (1-236): 1.25e-98: 288: 100.00		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Hs
		401111 RLA0_HUMAN (22-236): 2.82e-74: 229: 24.55		RPF2_HUMAN (1-285): 3.52e-77: 238: 17.57
+	Sc
		703048 MRT4_YEAST (1-236): 1.25e-98: 288: 100.00		RPF1_YEAST (4-252): 5.84e-52: 173: 14.40
+	Hs
		401035 RLA0_HUMAN (22-236): 2.82e-74: 229: 24.55		IMP4_HUMAN (13-255): 9.01e-73: 227: 15.79
+	Hs
		401116 RLA0_HUMAN (22-236): 2.82e-74: 229: 24.55		RPF1_HUMAN (7-251): 6.1e-62: 201: 17.13
+	Sc
		703046 MRT4_YEAST (1-236): 1.25e-98: 288: 100.00		SSF1_YEAST (10-197): 9.05e-34: 129: 15.64
+	Sc
		399418 RLA0_YEAST (20-236): 8.39e-66: 208: 23.87		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Hs
		401129 RLA0_HUMAN (22-236): 2.82e-74: 229: 24.55		SSF1_HUMAN (12-281): 5.67e-45: 160: 12.87
+	Sc
		399456 RLA0_YEAST (20-236): 8.39e-66: 208: 23.87		SSF1_YEAST (10-197): 9.05e-34: 129: 15.64