Protein: TEAD1
Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13)

Gene: TEAD1
Organism: Homo sapiens
Interactions: 170
UniProt ID: P28347

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

703107

YAP1
Transcriptional coactivator YAP1

20

20

Small-scale

0.988

High

703135

VGLL4
Transcription cofactor vestigial-like protein 4

5

4

Small-scale

0.930

High

703145

TEAD4
Transcriptional enhancer factor TEF-3

3

6

High-throughput

0.861

High

703146

TEAD2
Transcriptional enhancer factor TEF-4

2

6

High-throughput

0.811

High

71094

VGLL3
Transcription cofactor vestigial-like protein 3

2

12

High-throughput

0.783

High

703197

WWTR1
WW domain-containing transcription regulator protein 1

6

19

High-throughput

0.733

High

703193

VGLL1
Transcription cofactor vestigial-like protein 1

1

11

Small-scale

0.680

High

703098

TEAD1
Transcriptional enhancer factor TEF-1

1

6

Small-scale

0.647

High

703128

RAD51
DNA repair protein RAD51 homolog 1

3

0

High-throughput

0.634

High

703112

ATX1
Ataxin-1

2

1

High-throughput

0.601

High

429356

JUN
Transcription factor Jun

2

2

Small-scale

0.594

High

142850

NFIB
Nuclear factor 1 B-type

2

6

High-throughput

0.584

High

385476

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

4

High-throughput

0.584

High

473806

NFIC
Nuclear factor 1 C-type

2

7

High-throughput

0.584

High

703108

SOX2
Transcription factor SOX-2

2

4

High-throughput

0.584

High

703124

TLE3
Transducin-like enhancer protein 3

2

3

High-throughput

0.584

High

703130

NFIA
Nuclear factor 1 A-type

2

7

High-throughput

0.584

High

703189

CIC
Protein capicua homolog

2

4

High-throughput

0.584

High

549288

SRF
Serum response factor

1

2

Small-scale

0.578

High

703114

MAX
Protein max

1

2

Small-scale

0.561

High

703126

MEF2C
Myocyte-specific enhancer factor 2C

1

3

Small-scale

0.561

High

279024

TRIM3
Tripartite motif-containing protein 3

2

4

High-throughput

0.553

High

439651

INSR
Insulin receptor

1

1

High-throughput

0.541

High

583999

FOSL1
Fos-related antigen 1

1

1

Small-scale

0.536

High

595691

H13
Histone H1.3

1

1

High-throughput

0.536

High

605050

JUND
Transcription factor JunD

1

2

Small-scale

0.536

High

288224

KBL
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

1

0

High-throughput

0.518

High

445748

ENOA
Alpha-enolase

1

0

High-throughput

0.518

High

703184

OPTN
Optineurin

1

1

High-throughput

0.515

High

703196

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.515

High

703125

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.513

High

576169

PO2F1
POU domain, class 2, transcription factor 1

1

5

Small-scale

0.501

High

703148

NCOA1
Nuclear receptor coactivator 1

1

3

Small-scale

0.501

High

703166

ZDH17
Palmitoyltransferase ZDHHC17

1

2

High-throughput

0.494

High

703103

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

703105

HD
Huntingtin

1

0

High-throughput

0.493

High

703110

DYN2
Dynamin-2

1

0

High-throughput

0.493

High

703220

RNF11
RING finger protein 11

1

0

High-throughput

0.493

High

299740

MPDZ
Multiple PDZ domain protein

1

2

High-throughput

0.489

High

703100

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

703137

SRC8
Src substrate cortactin

1

1

High-throughput

0.489

High

628706

TBP
TATA-box-binding protein

1

0

Small-scale

0.480

High

154632

ARI1A
AT-rich interactive domain-containing protein 1A

1

8

High-throughput

0.479

High

161414

KMT2D
Histone-lysine N-methyltransferase 2D

1

4

High-throughput

0.479

High

174313

ZN609
Zinc finger protein 609

1

3

High-throughput

0.479

High

177439

ZN536
Zinc finger protein 536

1

3

High-throughput

0.479

High

179149

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

1

Small-scale

0.479

High

194513

KDM6A
Lysine-specific demethylase 6A

1

1

High-throughput

0.479

High

209954

CRX
Cone-rod homeobox protein

1

1

High-throughput

0.479

High

245592

ZEB2
Zinc finger E-box-binding homeobox 2

1

2

High-throughput

0.479

High

277152

ZN217
Zinc finger protein 217

1

3

High-throughput

0.479

High

344874

WIZ
Protein Wiz

1

1

High-throughput

0.479

High

467875

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

1

High-throughput

0.479

High

505520

ATX1L
Ataxin-1-like

1

1

High-throughput

0.479

High

555341

SKI
Ski oncogene

1

1

Small-scale

0.479

High

559728

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

2

High-throughput

0.479

High

578389

BRAF
Serine/threonine-protein kinase B-raf

1

2

High-throughput

0.479

High

604788

HXB9
Homeobox protein Hox-B9

1

5

High-throughput

0.479

High

703101

HXA10
Homeobox protein Hox-A10

1

7

High-throughput

0.479

High

703102

ZEB1
Zinc finger E-box-binding homeobox 1

1

2

High-throughput

0.479

High

703104

CUX1
Homeobox protein cut-like 1

1

4

High-throughput

0.479

High

703106

NKX21
Homeobox protein Nkx-2.1

1

1

High-throughput

0.479

High

703111

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

6

High-throughput

0.479

High

703115

H4
Histone H4

1

2

High-throughput

0.479

High

703117

H31
Histone H3.1

1

1

High-throughput

0.479

High

703118

SSBP2
Single-stranded DNA-binding protein 2

1

1

High-throughput

0.479

High

703119

H33
Histone H3.3

1

1

High-throughput

0.479

High

703120

FOXK2
Forkhead box protein K2

1

2

High-throughput

0.479

High

703122

SATB1
DNA-binding protein SATB1

1

3

High-throughput

0.479

High

703123

TLE1
Transducin-like enhancer protein 1

1

3

High-throughput

0.479

High

703127

RING1
E3 ubiquitin-protein ligase RING1

1

1

High-throughput

0.479

High

703129

BPTF
Nucleosome-remodeling factor subunit BPTF

1

2

High-throughput

0.479

High

703131

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

4

High-throughput

0.479

High

703132

FOXC1
Forkhead box protein C1

1

2

High-throughput

0.479

High

703133

RLF
Zinc finger protein Rlf

1

1

High-throughput

0.479

High

703134

SKP2
S-phase kinase-associated protein 2

1

1

Small-scale

0.479

High

703136

TFDP1
Transcription factor Dp-1

1

1

High-throughput

0.479

High

703138

SMC1A
Structural maintenance of chromosomes protein 1A

1

3

High-throughput

0.479

High

703141

MEF2D
Myocyte-specific enhancer factor 2D

1

2

High-throughput

0.479

High

703142

ARI5B
AT-rich interactive domain-containing protein 5B

1

8

High-throughput

0.479

High

703143

NFIX
Nuclear factor 1 X-type

1

7

High-throughput

0.479

High

703150

ZFHX3
Zinc finger homeobox protein 3

1

2

High-throughput

0.479

High

703152

ARI4B
AT-rich interactive domain-containing protein 4B

1

8

High-throughput

0.479

High

703154

TSH3
Teashirt homolog 3

1

3

High-throughput

0.479

High

703155

ARID2
AT-rich interactive domain-containing protein 2

1

9

High-throughput

0.479

High

703156

NIPBL
Nipped-B-like protein

1

1

High-throughput

0.479

High

703157

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

1

High-throughput

0.479

High

703158

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

3

High-throughput

0.479

High

703159

BCOR
BCL-6 corepressor

1

2

High-throughput

0.479

High

703160

PAXI1
PAX-interacting protein 1

1

2

High-throughput

0.479

High

703161

ASXL2
Putative Polycomb group protein ASXL2

1

2

High-throughput

0.479

High

703162

I2BP2
Interferon regulatory factor 2-binding protein 2

1

2

High-throughput

0.479

High

703163

PB1
Protein polybromo-1

1

2

High-throughput

0.479

High

703164

ZFHX4
Zinc finger homeobox protein 4

1

2

High-throughput

0.479

High

703165

I2BP1
Interferon regulatory factor 2-binding protein 1

1

1

High-throughput

0.479

High

703167

ARI3B
AT-rich interactive domain-containing protein 3B

1

8

High-throughput

0.479

High

703168

MGAP
MAX gene-associated protein

1

2

High-throughput

0.479

High

703171

KMT2C
Histone-lysine N-methyltransferase 2C

1

5

High-throughput

0.479

High

703172

ARI1B
AT-rich interactive domain-containing protein 1B

1

9

High-throughput

0.479

High

703174

KDM2B
Lysine-specific demethylase 2B

1

1

High-throughput

0.479

High

703175

PHF10
PHD finger protein 10

1

5

High-throughput

0.479

High

703176

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

1

High-throughput

0.479

High

703177

ZN516
Zinc finger protein 516

1

3

High-throughput

0.479

High

703179

REQU
Zinc finger protein ubi-d4

1

5

High-throughput

0.479

High

703180

CBP
CREB-binding protein

1

3

High-throughput

0.479

High

703181

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

4

High-throughput

0.479

High

703182

ZKSC4
Zinc finger protein with KRAB and SCAN domains 4

1

1

High-throughput

0.479

High

703183

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

1

High-throughput

0.479

High

703185

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

3

High-throughput

0.479

High

703188

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

1

High-throughput

0.479

High

703191

RING2
E3 ubiquitin-protein ligase RING2

1

3

High-throughput

0.479

High

703192

ARI3A
AT-rich interactive domain-containing protein 3A

1

8

High-throughput

0.479

High

703194

KIFC1
Kinesin-like protein KIFC1

1

1

High-throughput

0.479

High

703195

SSBP3
Single-stranded DNA-binding protein 3

1

2

High-throughput

0.479

High

703198

FOXP1
Forkhead box protein P1

1

2

High-throughput

0.479

High

703199

ZN644
Zinc finger protein 644

1

1

High-throughput

0.479

High

703200

ZN703
Zinc finger protein 703

1

1

High-throughput

0.479

High

703201

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

1

High-throughput

0.479

High

703204

HM20A
High mobility group protein 20A

1

3

High-throughput

0.479

High

703205

BRD7
Bromodomain-containing protein 7

1

2

High-throughput

0.479

High

703206

TF7L2
Transcription factor 7-like 2

1

4

High-throughput

0.479

High

703207

SALL1
Sal-like protein 1

1

1

High-throughput

0.479

High

703209

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

4

High-throughput

0.479

High

703210

RCOR3
REST corepressor 3

1

2

High-throughput

0.479

High

703212

TRPS1
Zinc finger transcription factor Trps1

1

1

High-throughput

0.479

High

703213

DACH1
Dachshund homolog 1

1

1

High-throughput

0.479

High

703214

ZN608
Zinc finger protein 608

1

1

High-throughput

0.479

High

703215

PRR12
Proline-rich protein 12

1

3

High-throughput

0.479

High

703216

SATB2
DNA-binding protein SATB2

1

3

High-throughput

0.479

High

703217

SMC3
Structural maintenance of chromosomes protein 3

1

3

High-throughput

0.479

High

703218

ZN148
Zinc finger protein 148

1

1

High-throughput

0.479

High

703219

ZN281
Zinc finger protein 281

1

1

High-throughput

0.479

High

703221

ZSC21
Zinc finger and SCAN domain-containing protein 21

1

1

High-throughput

0.479

High

703222

NCOR2
Nuclear receptor corepressor 2

1

3

High-throughput

0.479

High

703223

ZHX2
Zinc fingers and homeoboxes protein 2

1

4

High-throughput

0.479

High

65700

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

0

High-throughput

0.458

High

261370

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

0

High-throughput

0.458

High

297757

PIAS2
E3 SUMO-protein ligase PIAS2

1

0

High-throughput

0.458

High

586228

ZEP1
Zinc finger protein 40

1

0

High-throughput

0.458

High

675378

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.458

High

703109

CTCF
Transcriptional repressor CTCF

1

0

High-throughput

0.458

High

703113

MAZ
Myc-associated zinc finger protein

1

0

High-throughput

0.458

High

703121

TFAP4
Transcription factor AP-4

1

0

High-throughput

0.458

High

703140

CBX2
Chromobox protein homolog 2

1

0

High-throughput

0.458

High

703144

RBBP5
Retinoblastoma-binding protein 5

1

0

High-throughput

0.458

High

703147

ELF2
ETS-related transcription factor Elf-2

1

0

High-throughput

0.458

High

703170

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.458

High

703173

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

703178

RREB1
Ras-responsive element-binding protein 1

1

0

High-throughput

0.458

High

703186

ZN462
Zinc finger protein 462

1

0

High-throughput

0.458

High

703187

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

0

High-throughput

0.458

High

703190

UIMC1
BRCA1-A complex subunit RAP80

1

0

High-throughput

0.458

High

703211

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

703224

MORC2
ATPase MORC2

1

0

High-throughput

0.458

High

156985

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.437

High

703169

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

703153

HS905
Putative heat shock protein HSP 90-alpha A5

1

3

High-throughput

0.407

High

703151

TAZ
Tafazzin

2

0

Small-scale

0.325

High

700773

DMB
HLA class II histocompatibility antigen, DM beta chain

1

0

High-throughput

0.282

High

703149

TBCC
Tubulin-specific chaperone C

1

0

High-throughput

0.279

Low

703208

TMOD2
Tropomodulin-2

1

0

High-throughput

0.279

Low

301352

WFS1
Wolframin

1

0

High-throughput

0.268

Low

369623

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.268

Low

456194

CATD
Cathepsin D

1

0

High-throughput

0.268

Low

703099

GRN
Progranulin

1

0

High-throughput

0.268

Low

703116

TPM4
Tropomyosin alpha-4 chain

1

0

High-throughput

0.261

Low

703202

UBTD1
Ubiquitin domain-containing protein 1

1

0

Small-scale

0.251

Low

703139

GSE1
Genetic suppressor element 1

1

0

High-throughput

0.249

Low

703203

FBSL
Fibrosin-1-like protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025