HitPredict

Interactor 1: CSTF2 (P33240)
Cleavage stimulation factor subunit 2 (CF-1 64 kDa subunit) (Cleavage stimulation factor 64 kDa subunit) (CSTF 64 kDa subunit) (CstF-64)
Gene: CSTF2

Interactor 2: CPSF2 (Q9P2I0)
Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit)
Gene: CPSF2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	10669729, 18688255
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 577 Hs			1 782
+	Hs
		1327896 CSTFT_HUMAN (1-576): 3.87e-55: 198: 67.64		CPSF2_HUMAN (1-782): 0: 952: 100.00
+	Dm
		1358431 Q9VE52_DROME (1-330): 2.62e-55: 194: 47.61		CPSF2_DROME (1-782): 0: 764: 53.50
+	Hs
		703456 CSTF2_HUMAN (1-577): 6.95e-81: 266: 100.00		CPSF3_HUMAN (2-558): 1.85e-173: 516: 21.28
+	Hs
		1327901 CSTFT_HUMAN (1-576): 3.87e-55: 198: 67.64		CPSF3_HUMAN (2-558): 1.85e-173: 516: 21.28
+	Dm
		1364308 Q9VE52_DROME (1-330): 2.62e-55: 194: 47.61		CPSF3_DROME (2-530): 4.61e-174: 518: 21.83
+	Sc
		376934 PABP_YEAST (2-199): 1.13e-27: 119: 17.41		YSH1_YEAST (2-538): 1.74e-145: 447: 21.07
+	Sp
		142954 CTF1_SCHPO (18-100): 1.37e-16: 83.6: 49.40		YSH1_SCHPO (2-540): 3.17e-158: 480: 21.28
+	Sc
		628801 RNA15_YEAST (16-88): 7.2e-16: 80.5: 47.95		CFT2_YEAST (1-780): 7.18e-156: 477: 20.61
+	Sc
		628796 RNA15_YEAST (16-88): 7.2e-16: 80.5: 47.95		YSH1_YEAST (2-538): 1.74e-145: 447: 21.07