Protein: FPR1
fMet-Leu-Phe receptor (fMLP receptor) (N-formyl peptide receptor) (FPR) (N-formylpeptide chemoattractant receptor)

Gene: FPR1
Organism: Homo sapiens
Interactions: 224
UniProt ID: P21462

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0002430 - complement receptor mediated signaling pathway
GO:0004875 - complement receptor activity
GO:0004930 - G protein-coupled receptor activity
GO:0004982 - N-formyl peptide receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

638468

WDFY3
WD repeat and FYVE domain-containing protein 3

2

6

High-throughput

0.776

High

184578

MK13
Mitogen-activated protein kinase 13

1

5

Small-scale

0.691

High

316598

ST17B
Serine/threonine-protein kinase 17B

1

5

High-throughput

0.691

High

638390

ARBK1
Beta-adrenergic receptor kinase 1

1

13

Small-scale

0.691

High

638392

TTK
Dual specificity protein kinase TTK

1

7

High-throughput

0.691

High

638413

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

1

1

High-throughput

0.691

High

638464

VRK2
Serine/threonine-protein kinase VRK2

1

1

High-throughput

0.691

High

638512

LST8
Target of rapamycin complex subunit LST8

1

0

High-throughput

0.656

High

638393

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

6

High-throughput

0.618

High

638479

DMXL2
DmX-like protein 2

1

5

High-throughput

0.618

High

638391

MK03
Mitogen-activated protein kinase 3

1

2

Small-scale

0.618

High

187461

FANCA
Fanconi anemia group A protein

2

5

High-throughput

0.601

High

208018

TTI1
TELO2-interacting protein 1 homolog

2

3

High-throughput

0.601

High

212871

AP5Z1
AP-5 complex subunit zeta-1

2

1

High-throughput

0.601

High

248558

FADS1
Acyl-CoA

2

9

High-throughput

0.601

High

252826

EXOC3
Exocyst complex component 3

2

5

High-throughput

0.601

High

318111

IPO13
Importin-13

2

20

High-throughput

0.601

High

319393

UFL1
E3 UFM1-protein ligase 1

2

3

High-throughput

0.601

High

638394

MTOR
Serine/threonine-protein kinase mTOR

2

20

High-throughput

0.601

High

638398

KNTC1
Kinetochore-associated protein 1

2

3

High-throughput

0.601

High

638408

ATM
Serine-protein kinase ATM

2

20

High-throughput

0.601

High

638442

RN213
E3 ubiquitin-protein ligase RNF213

2

2

High-throughput

0.601

High

638443

TBC9B
TBC1 domain family member 9B

2

6

High-throughput

0.601

High

638452

BRAT1
Integrator complex assembly factor BRAT1

2

3

High-throughput

0.601

High

638465

DAAF5
Dynein axonemal assembly factor 5

2

7

High-throughput

0.601

High

638466

IPRI
Inositol 1,4,5-trisphosphate receptor-interacting protein

2

3

High-throughput

0.601

High

638470

INT1
Integrator complex subunit 1

2

7

High-throughput

0.601

High

638478

CIP2A
Protein CIP2A

2

6

High-throughput

0.601

High

638482

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

2

7

High-throughput

0.601

High

638496

RUSF1
RUS family member 1

2

2

High-throughput

0.601

High

638499

COG3
Conserved oligomeric Golgi complex subunit 3

2

2

High-throughput

0.601

High

638500

SPTCS
Spatacsin

2

3

High-throughput

0.601

High

638503

EXOC2
Exocyst complex component 2

2

8

High-throughput

0.601

High

638518

INT2
Integrator complex subunit 2

2

4

High-throughput

0.601

High

638540

ERAP1
Endoplasmic reticulum aminopeptidase 1

2

6

High-throughput

0.601

High

638545

GCP4
Gamma-tubulin complex component 4

2

16

High-throughput

0.601

High

638548

XPO7
Exportin-7

2

20

High-throughput

0.601

High

638554

EXOC7
Exocyst complex component 7

2

2

High-throughput

0.601

High

638562

TNPO3
Transportin-3

2

20

High-throughput

0.601

High

167820

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

5

High-throughput

0.575

High

177794

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

5

High-throughput

0.575

High

638509

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

4

High-throughput

0.575

High

638566

M3K4
Mitogen-activated protein kinase kinase kinase 4

1

2

High-throughput

0.575

High

638395

PI4KA
Phosphatidylinositol 4-kinase alpha

2

13

High-throughput

0.552

High

173653

BTAF1
TATA-binding protein-associated factor 172

2

11

High-throughput

0.549

High

244315

NPA1P
Nucleolar pre-ribosomal-associated protein 1

2

1

High-throughput

0.549

High

638435

SYAM
Alanine--tRNA ligase, mitochondrial

2

2

High-throughput

0.549

High

638437

SYRM
Probable arginine--tRNA ligase, mitochondrial

2

2

High-throughput

0.549

High

638448

TTI2
TELO2-interacting protein 2

2

4

High-throughput

0.549

High

638454

THADA
tRNA

2

6

High-throughput

0.549

High

638471

VPS8
Vacuolar protein sorting-associated protein 8 homolog

2

2

High-throughput

0.549

High

638481

COG1
Conserved oligomeric Golgi complex subunit 1

2

2

High-throughput

0.549

High

638514

FACD2
Fanconi anemia group D2 protein

2

7

High-throughput

0.549

High

638525

COG4
Conserved oligomeric Golgi complex subunit 4

2

3

High-throughput

0.549

High

638547

IPO11
Importin-11

2

16

High-throughput

0.549

High

638555

UBP24
Ubiquitin carboxyl-terminal hydrolase 24

2

6

High-throughput

0.549

High

638559

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.546

High

170480

RAB7L
Ras-related protein Rab-7L1

1

9

High-throughput

0.536

High

172470

XPO1
Exportin-1

1

20

High-throughput

0.536

High

189108

IPO8
Importin-8

1

14

High-throughput

0.536

High

211729

ZW10
Centromere/kinetochore protein zw10 homolog

1

5

High-throughput

0.536

High

220054

XRCC2
DNA repair protein XRCC2

1

3

High-throughput

0.536

High

226398

SNG2
Synaptogyrin-2

1

5

High-throughput

0.536

High

271665

HIP1R
Huntingtin-interacting protein 1-related protein

1

4

High-throughput

0.536

High

292333

RA51D
DNA repair protein RAD51 homolog 4

1

3

High-throughput

0.536

High

609574

LEG3
Galectin-3

1

3

High-throughput

0.536

High

638397

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

4

High-throughput

0.536

High

638400

CTR2
Cationic amino acid transporter 2

1

17

High-throughput

0.536

High

638402

AT12A
Potassium-transporting ATPase alpha chain 2

1

20

High-throughput

0.536

High

638403

XPO2
Exportin-2

1

17

High-throughput

0.536

High

638404

PEX3
Peroxisomal biogenesis factor 3

1

3

High-throughput

0.536

High

638405

GEMI4
Gem-associated protein 4

1

2

High-throughput

0.536

High

638406

RAB38
Ras-related protein Rab-38

1

9

High-throughput

0.536

High

638407

PRKDC
DNA-dependent protein kinase catalytic subunit

1

17

High-throughput

0.536

High

638410

MTX1
Metaxin-1

1

7

High-throughput

0.536

High

638423

NOMO1
BOS complex subunit NOMO1

1

5

High-throughput

0.536

High

638425

MSMO1
Methylsterol monooxygenase 1

1

8

High-throughput

0.536

High

638426

OCLN
Occludin

1

1

High-throughput

0.536

High

638427

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

12

High-throughput

0.536

High

638428

TBB8
Tubulin beta-8 chain

1

5

High-throughput

0.536

High

638432

PKHG4
Puratrophin-1

1

3

High-throughput

0.536

High

638439

RIF1
Telomere-associated protein RIF1

1

5

High-throughput

0.536

High

638441

ECM29
Proteasome adapter and scaffold protein ECM29

1

12

High-throughput

0.536

High

638444

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

9

High-throughput

0.536

High

638446

ATLA3
Atlastin-3

1

13

High-throughput

0.536

High

638461

DYM
Dymeclin

1

8

High-throughput

0.536

High

638473

SIMC1
SUMO-interacting motif-containing protein 1

1

2

High-throughput

0.536

High

638474

T161B
Transmembrane protein 161B

1

8

High-throughput

0.536

High

638475

NAV1
Neuron navigator 1

1

4

High-throughput

0.536

High

638476

ATLA2
Atlastin-2

1

13

High-throughput

0.536

High

638477

EXOC6
Exocyst complex component 6

1

5

High-throughput

0.536

High

638485

LGAT1
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

1

10

High-throughput

0.536

High

638486

GCN1
Stalled ribosome sensor GCN1

1

15

High-throughput

0.536

High

638487

CDS1
Phosphatidate cytidylyltransferase 1

1

2

High-throughput

0.536

High

638492

COQ8B
Atypical kinase COQ8B, mitochondrial

1

11

High-throughput

0.536

High

638493

RB39B
Ras-related protein Rab-39B

1

8

High-throughput

0.536

High

638494

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

1

High-throughput

0.536

High

638502

CLMN
Calmin

1

3

High-throughput

0.536

High

638504

XPO6
Exportin-6

1

5

High-throughput

0.536

High

638506

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

3

High-throughput

0.536

High

638507

TM209
Transmembrane protein 209

1

1

High-throughput

0.536

High

638510

GCP2
Gamma-tubulin complex component 2

1

16

High-throughput

0.536

High

638515

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

1

High-throughput

0.536

High

638517

XPO4
Exportin-4

1

20

High-throughput

0.536

High

638526

XPO5
Exportin-5

1

20

High-throughput

0.536

High

638529

RAB18
Ras-related protein Rab-18

1

8

High-throughput

0.536

High

638534

MITOS
Mitochondrial potassium channel ATP-binding subunit

1

4

High-throughput

0.536

High

638546

VATH
V-type proton ATPase subunit H

1

2

High-throughput

0.536

High

638550

CNOT7
CCR4-NOT transcription complex subunit 7

1

1

High-throughput

0.536

High

638551

AMFR
E3 ubiquitin-protein ligase AMFR

1

3

High-throughput

0.536

High

638552

TMCO1
Calcium load-activated calcium channel

1

6

High-throughput

0.536

High

638561

TELO2
Telomere length regulation protein TEL2 homolog

1

2

High-throughput

0.536

High

638563

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

10

High-throughput

0.536

High

638565

EPN1
Epsin-1

1

2

High-throughput

0.536

High

638415

EFR3A
Protein EFR3 homolog A

1

0

High-throughput

0.513

High

638483

IP6K1
Inositol hexakisphosphate kinase 1

1

0

High-throughput

0.513

High

638484

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.513

High

638516

TB182
182 kDa tankyrase-1-binding protein

1

0

High-throughput

0.513

High

185159

FANCG
Fanconi anemia group G protein

1

1

High-throughput

0.489

High

335599

AGM1
Phosphoacetylglucosamine mutase

1

2

High-throughput

0.489

High

425769

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

1

High-throughput

0.489

High

638416

COG2
Conserved oligomeric Golgi complex subunit 2

1

3

High-throughput

0.489

High

638419

OXA1L
Mitochondrial inner membrane protein OXA1L

1

4

High-throughput

0.489

High

638421

PDK1
[Pyruvate dehydrogenase

1

5

High-throughput

0.489

High

638422

PDK3
[Pyruvate dehydrogenase

1

5

High-throughput

0.489

High

638430

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

12

High-throughput

0.489

High

638433

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

3

High-throughput

0.489

High

638434

SYEM
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial

1

2

High-throughput

0.489

High

638438

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

1

9

High-throughput

0.489

High

638449

MZT2B
Mitotic-spindle organizing protein 2B

1

5

High-throughput

0.489

High

638450

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

7

High-throughput

0.489

High

638459

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

12

High-throughput

0.489

High

638460

DPH6
Diphthine--ammonia ligase

1

4

High-throughput

0.489

High

638463

ADCK1
AarF domain-containing protein kinase 1

1

11

High-throughput

0.489

High

638541

ORML1
ORM1-like protein 1

1

2

High-throughput

0.489

High

638544

CNOT8
CCR4-NOT transcription complex subunit 8

1

1

High-throughput

0.489

High

638553

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

2

High-throughput

0.489

High

638558

COG6
Conserved oligomeric Golgi complex subunit 6

1

1

High-throughput

0.489

High

638560

DOP1B
Protein DOP1B

1

1

High-throughput

0.489

High

638564

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

10

High-throughput

0.489

High

402852

ANXA1
Annexin A1

1

2

Small-scale

0.479

High

638420

RAGE
Advanced glycosylation end product-specific receptor

1

5

Small-scale

0.479

High

60298

NBAS
NBAS subunit of NRZ tethering complex

1

1

High-throughput

0.445

High

133725

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

2

High-throughput

0.445

High

137181

EXOC5
Exocyst complex component 5

1

3

High-throughput

0.445

High

161282

ENC1
Ectoderm-neural cortex protein 1

1

2

High-throughput

0.445

High

231678

PEX1
Peroxisomal ATPase PEX1

1

1

High-throughput

0.445

High

245420

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

5

High-throughput

0.445

High

269510

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

6

High-throughput

0.445

High

273486

DJC13
DnaJ homolog subfamily C member 13

1

1

High-throughput

0.445

High

326921

UBE4B
Ubiquitin conjugation factor E4 B

1

3

High-throughput

0.445

High

637840

NF1
Neurofibromin

1

4

High-throughput

0.445

High

638396

HD
Huntingtin

1

4

High-throughput

0.445

High

638399

CLCN7
H(+)/Cl(-) exchange transporter 7

1

1

High-throughput

0.445

High

638401

STAT2
Signal transducer and activator of transcription 2

1

8

High-throughput

0.445

High

638411

STIM1
Stromal interaction molecule 1

1

1

High-throughput

0.445

High

638417

CUL7
Cullin-7

1

2

High-throughput

0.445

High

638418

LRC14
Leucine-rich repeat-containing protein 14

1

2

High-throughput

0.445

High

638431

TM177
Transmembrane protein 177

1

1

High-throughput

0.445

High

638453

LRRN1
Leucine-rich repeat neuronal protein 1

1

1

High-throughput

0.445

High

638455

NBEL2
Neurobeachin-like protein 2

1

6

High-throughput

0.445

High

638458

UN13D
Protein unc-13 homolog D

1

6

High-throughput

0.445

High

638462

WAPL
Wings apart-like protein homolog

1

2

High-throughput

0.445

High

638480

PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

1

1

High-throughput

0.445

High

638488

EXOC4
Exocyst complex component 4

1

4

High-throughput

0.445

High

638490

OTUL
Ubiquitin thioesterase otulin

1

3

High-throughput

0.445

High

638495

HOOK2
Protein Hook homolog 2

1

6

High-throughput

0.445

High

638497

INT4
Integrator complex subunit 4

1

1

High-throughput

0.445

High

638498

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

7

High-throughput

0.445

High

638505

PANX1
Pannexin-1

1

3

High-throughput

0.445

High

638508

RUFY1
RUN and FYVE domain-containing protein 1

1

6

High-throughput

0.445

High

638511

NDC1
Nucleoporin NDC1

1

4

High-throughput

0.445

High

638519

AMPB
Aminopeptidase B

1

6

High-throughput

0.445

High

638520

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

1

High-throughput

0.445

High

638521

HEAT1
HEAT repeat-containing protein 1

1

2

High-throughput

0.445

High

638527

EPG5
Ectopic P granules protein 5 homolog

1

1

High-throughput

0.445

High

638528

SYF1
Pre-mRNA-splicing factor SYF1

1

2

High-throughput

0.445

High

638533

MDN1
Midasin

1

4

High-throughput

0.445

High

638535

OTULL
Inactive ubiquitin thioesterase OTULINL

1

3

High-throughput

0.445

High

638536

EXOC1
Exocyst complex component 1

1

3

High-throughput

0.445

High

638538

ABI2
Abl interactor 2

1

6

High-throughput

0.445

High

638539

ELOV5
Very long chain fatty acid elongase 5

1

9

High-throughput

0.445

High

638543

AASS
Alpha-aminoadipic semialdehyde synthase, mitochondrial

1

1

High-throughput

0.445

High

638549

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

12

High-throughput

0.445

High

506550

GPHRB
Golgi pH regulator B

1

17

High-throughput

0.437

High

638429

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

11

High-throughput

0.437

High

442586

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.426

High

449559

HEXA
Beta-hexosaminidase subunit alpha

1

0

High-throughput

0.426

High

638409

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

0

High-throughput

0.426

High

638489

FERM2
Fermitin family homolog 2

1

0

High-throughput

0.426

High

638501

ELMO2
Engulfment and cell motility protein 2

1

0

High-throughput

0.426

High

85333

GPHRA
Golgi pH regulator A

1

17

High-throughput

0.407

High

273159

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

15

High-throughput

0.407

High

273647

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

2

High-throughput

0.407

High

288220

KBL
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

1

2

High-throughput

0.407

High

317440

GFPT2
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2

1

2

High-throughput

0.407

High

341236

ASML
Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase

1

1

High-throughput

0.407

High

638414

URB2
Unhealthy ribosome biogenesis protein 2 homolog

1

3

High-throughput

0.407

High

638445

ZFY26
Zinc finger FYVE domain-containing protein 26

1

6

High-throughput

0.407

High

638447

RINT1
RAD50-interacting protein 1

1

7

High-throughput

0.407

High

638451

PGM2L
Glucose 1,6-bisphosphate synthase

1

4

High-throughput

0.407

High

638456

TBCD9
TBC1 domain family member 9

1

6

High-throughput

0.407

High

638457

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

1

6

High-throughput

0.407

High

638467

CUL9
Cullin-9

1

2

High-throughput

0.407

High

638491

INT12
Integrator complex subunit 12

1

5

High-throughput

0.407

High

638523

ZWILC
Protein zwilch homolog

1

2

High-throughput

0.407

High

638530

HELLS
Lymphoid-specific helicase

1

3

High-throughput

0.407

High

638531

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

1

13

High-throughput

0.407

High

638532

ECHD1
Ethylmalonyl-CoA decarboxylase

1

5

High-throughput

0.407

High

638556

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

3

High-throughput

0.407

High

638436

SYVM
Valine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

638469

FCSK
L-fucose kinase

1

0

High-throughput

0.279

Low

638472

ANR44
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B

1

0

High-throughput

0.279

Low

638537

PANK4
4'-phosphopantetheine phosphatase

1

0

High-throughput

0.279

Low

282353

MED24
Mediator of RNA polymerase II transcription subunit 24

1

0

High-throughput

0.232

Low

321888

FRYL
Protein furry homolog-like

1

0

High-throughput

0.232

Low

638412

NCOA4
Nuclear receptor coactivator 4

1

0

High-throughput

0.232

Low

638424

SKI2
Superkiller complex protein 2

1

0

High-throughput

0.232

Low

638440

FOCAD
Focadhesin

1

0

High-throughput

0.232

Low

638513

RPAP1
RNA polymerase II-associated protein 1

1

0

High-throughput

0.232

Low

638522

UBE2Z
Ubiquitin-conjugating enzyme E2 Z

1

0

High-throughput

0.232

Low

638524

ARMT1
Damage-control phosphatase ARMT1

1

0

High-throughput

0.232

Low

638542

RELCH
RAB11-binding protein RELCH

1

0

High-throughput

0.232

Low

638557

NCKP1
Nck-associated protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025